X0202 SCHEDULE 13G 0001756235 XXXXXXXX LIVE Common Stock, par value $0.0001 per share 07/22/2026 0001946563 60 DEGREES PHARMACEUTICALS, INC. 83006G104 1025 Connecticut Avenue NW Suite 1000 Washington DC 20036 Rule 13d-1(c) Knight Therapeutics Inc. Z4 658629.00 0.00 658629.00 0.00 658629.00 N 19.85 CO (1) Based on 2,659,288 shares of common stock, par value $0.0001 per share, of 60 Degrees Pharmaceuticals, Inc. (the "Issuer") that are issued and outstanding as of May 15, 2026, as reported by the Issuer in its quarterly report on Form 10-Q filed with the U.S. Securities and Exchange Commission on May 15, 2026. 60 DEGREES PHARMACEUTICALS, INC. 1025 Connecticut Avenue, NW Suite 1000, Washington D.C. 20036 Knight Therapeutics Inc. 600 - 100 boul. Alexis Nihon Montreal, QC, H4M 2P2 Canada Y As of July 22, 2026, the Reporting Person beneficially owns 658,629 shares of common stock, par value $0.0001 per share, of the Issuer. 19.85%. The above percentage is calculated based on 2,659,288 shares of common stock, par value $0.0001 per share, of the Issuer that are issued and outstanding as of May 15, 2026, as reported by the Issuer in its quarterly report on Form 10-Q filed with the U.S. Securities and Exchange Commission on May 15, 2026. 658,629 shares of common stock of the Issuer 0 658,629 shares of common stock of the Issuer 0 Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11. Knight Therapeutics Inc. /s/ Samira Sakhia 07/28/2026