X0202 SCHEDULE 13G/A 0001738048-26-000004 0001738048 XXXXXXXX LIVE 1 Class A Ordinary Shares, par value US$0.0001 per share 06/30/2026 0001944552 Adlai Nortye Ltd. 00704R109 c/o PO Box 309, Ugland House Grand Cayman E9 KY1-1104 Rule 13d-1(c) Venrock Healthcare Capital Partners III, L.P. a DE 0.00 9638193.00 0.00 9638193.00 9638193.00 4.4 PN VHCP Co-Investment Holdings III, LLC a DE 0.00 9638193.00 0.00 9638193.00 9638193.00 4.4 OO Venrock Healthcare Capital Partners EG, L.P. a DE 0.00 9638193.00 0.00 9638193.00 9638193.00 4.4 PN VHCP Management III, LLC a DE 0.00 9638193.00 0.00 9638193.00 9638193.00 4.4 OO VHCP Management EG, LLC a DE 0.00 9638193.00 0.00 9638193.00 9638193.00 4.4 OO Nimish Shah a X1 0.00 9638193.00 0.00 9638193.00 9638193.00 4.4 IN Bong Y. Koh a X1 0.00 9638193.00 0.00 9638193.00 9638193.00 4.4 IN Adlai Nortye Ltd. c/o PO Box 309, Ugland House, Grand Cayman, E9, KY1-1104. The names of the persons filing this report (collectively, the "Reporting Persons") are: Venrock Healthcare Capital Partners III, L.P. ("VHCP III") VHCP Co-Investment Holdings III, LLC ("VHCP Co-Investment III") Venrock Healthcare Capital Partners EG, L.P. ("VHCP EG") VHCP Management III, LLC ("VHCP Management III") VHCP Management EG, LLC ("VHCP Management EG") Nimish Shah ("Shah") Bong Koh ("Koh") The Reporting Persons are members of a group for the purposes of this Schedule 13G/A. New York Office: 7 Bryant Park, 23rd Floor New York, NY 10018 Palo Alto Office: 3340 Hillview Avenue Palo Alto, CA 94304 All of the entities were organized in Delaware. Shah and Koh are both United States citizens. Y There is no CUSIP number assigned to the Class A ordinary shares. CUSIP number 00704R109 has been assigned to the American Depositary Shares ("ADS") of the Issuer. Each ADS represents three Class A ordinary shares. Row 9 of each Reporting Person's cover page to this Schedule 13G/A sets forth the aggregate number of Class A ordinary shares of the Issuer beneficially owned by such Reporting Person as of June 30, 2026 and is incorporated by reference. The Reporting Persons' ownership of the Issuer's securities consists of (i) 522,711 ADS, representing an aggregate of 1,568,133 Class A ordinary shares, held by VHCP III, (ii) 52,370 ADS, representing an aggregate of 157,110 Class A ordinary shares, held by VHCP Co-Investment III, and (iii) 2,637,650 ADS, representing an aggregate of 7,912,950 Class A ordinary shares, held by VHCP EG. VHCP Management III is the general partner of VHCP III and the manager of VHCP Co-Investment III. VHCP Management EG is the general partner of VHCP EG. Messrs. Shah and Koh are the voting members of VHCP Management III and VHCP Management EG. Row 11 of each Reporting Person's cover page to this Schedule 13G/A sets forth the percentages of Class A ordinary shares of the Issuer beneficially owned by such Reporting Person as of June 30, 2026 and is incorporated by reference. The percentage set forth in each row 11 is based upon 218,578,430 Class A ordinary shares outstanding as of April 21, 2026, as reported in the Issuer's Prospectus Supplement filed with the Securities and Exchange Commission (the "SEC") on July 20, 2026. Row 5 of each Reporting Person's cover page to this Schedule 13G/A sets forth the sole power to vote or to direct the vote of securities of the Issuer beneficially owned by such Reporting Person as of June 30, 2026 and is incorporated by reference. Row 6 of each Reporting Person's cover page to this Schedule 13G/A sets forth the shared power to vote or to direct the vote of securities of the Issuer beneficially owned by such Reporting Person as of June 30, 2026 and is incorporated by reference. Row 7 of each Reporting Person's cover page to this Schedule 13G/A sets forth the sole power to dispose or to direct the disposition of securities of the Issuer beneficially owned by such Reporting Person as of June 30, 2026 and is incorporated by reference. Row 8 of each Reporting Person's cover page to this Schedule 13G/A sets forth the shared power to dispose or to direct the disposition of securities of the Issuer beneficially owned by such Reporting Person as of June 30, 2026 and is incorporated by reference. N Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11. Exhibit 24.1 Power of Attorney for Bong Koh (incorporated by reference to Exhibit 24.1 to Schedule 13G filed on February 11, 2026) Exhibit 24.2 Power of Attorney for Nimish Shah (incorporated by reference to Exhibit 24.2 to Schedule 13G filed on February 11, 2026) Exhibit 99.1 Joint Filing Agreement (incorporated by reference to Exhibit 99.1 to Schedule 13G filed on February 11, 2026) Venrock Healthcare Capital Partners III, L.P. /s/ Sherman G. Souther 08/14/2026 VHCP Co-Investment Holdings III, LLC /s/ Sherman G. Souther 08/14/2026 Venrock Healthcare Capital Partners EG, L.P. /s/ Sherman G. Souther 08/14/2026 VHCP Management III, LLC /s/ Sherman G. Souther 08/14/2026 VHCP Management EG, LLC /s/ Sherman G. Souther 08/14/2026 Nimish Shah /s/ Sherman G. Souther 08/14/2026 Bong Y. Koh /s/ Sherman G. Souther 08/14/2026