NPORT-EX 2 canc.htm NPORT-EX

Tema Oncology ETF
 
Schedule of Investments
 
November 30, 2025 (Unaudited)
 
   
COMMON STOCKS - 98.6%
 
Shares
   
Value
 
Biotechnology - 67.7% (a)
       
AbbVie, Inc.
   
11,128
   
$
2,533,846
 
Amgen, Inc.
   
4,683
     
1,617,789
 
AnaptysBio, Inc. (b)
   
20,081
     
836,374
 
Arcellx, Inc. (b)
   
34,948
     
2,541,069
 
Arcus Biosciences, Inc. (b)
   
32,129
     
838,567
 
Argenx SE - ADR (b)
   
1,242
     
1,132,679
 
Ascentage Pharma Group International - ADR (b)
   
10,385
     
339,797
 
BeOne Medicines Ltd. - ADR (b)
   
7,179
     
2,445,239
 
BridgeBio Oncology Therapeutics, Inc. (b)
   
16,658
     
205,060
 
Bridgebio Pharma, Inc. (b)
   
64,050
     
4,612,241
 
Celcuity, Inc. (b)
   
27,354
     
2,766,584
 
CG oncology, Inc. (b)
   
32,061
     
1,437,615
 
Cogent Biosciences, Inc. (b)
   
101,162
     
4,068,736
 
Corvus Pharmaceuticals, Inc. (b)
   
62,806
     
575,931
 
Cullinan Therapeutics, Inc. (b)
   
32,857
     
373,584
 
Exelixis, Inc. (b)
   
68,039
     
3,005,283
 
Genmab AS - ADR (b)
   
123,261
     
3,988,726
 
Gilead Sciences, Inc.
   
16,672
     
2,098,004
 
Halozyme Therapeutics, Inc. (b)
   
16,616
     
1,186,382
 
Ideaya Biosciences, Inc. (b)
   
78,791
     
2,806,535
 
Immunocore Holdings PLC - ADR (b)
   
22,662
     
895,149
 
Immunome, Inc. (b)
   
85,852
     
1,581,394
 
Janux Therapeutics, Inc. (b)
   
42,799
     
1,459,018
 
Legend Biotech Corp. - ADR (b)
   
57,858
     
1,603,245
 
Nurix Therapeutics, Inc. (b)
   
68,115
     
1,204,273
 
Nuvalent, Inc. - Class A (b)
   
32,425
     
3,545,674
 
Olema Pharmaceuticals, Inc. (b)
   
39,584
     
1,121,019
 
ORIC Pharmaceuticals, Inc. (b)
   
24,783
     
294,422
 
Pyxis Oncology, Inc. (b)
   
41,743
     
216,646
 
Regeneron Pharmaceuticals, Inc.
   
1,910
     
1,490,163
 
Relay Therapeutics, Inc. (b)
   
99,160
     
785,347
 
Replimune Group, Inc. (b)
   
45,584
     
455,840
 
Revolution Medicines, Inc. (b)
   
102,315
     
7,956,014
 
Summit Therapeutics, Inc. (b)
   
85,163
     
1,523,566
 
Syndax Pharmaceuticals, Inc. (b)
   
114,677
     
2,272,898
 
UroGen Pharma Ltd. (b)
   
53,518
     
1,541,854
 
Xencor, Inc. (b)
   
53,760
     
931,123
 
Zai Lab Ltd. - ADR (b)
   
65,841
     
1,343,815
 
Zymeworks, Inc. (b)
   
67,539
     
1,803,967
 
             
71,435,468
 
                 
Health Care Providers & Services - 0.7%
         
Guardant Health, Inc. (b)
   
7,064
     
765,879
 
                 
Health Care Technology - 0.3%
         
Schrodinger, Inc. (b)
   
17,853
     
313,499
 
                 
Pharmaceuticals - 29.9% (a)
         
AstraZeneca PLC
   
22,973
     
4,249,394
 
Bristol-Myers Squibb Co.
   
50,771
     
2,497,933
 
Chugai Pharmaceutical Co. Ltd.
   
16,624
     
891,197
 
Daiichi Sankyo Co. Ltd.
   
47,798
     
1,182,366
 
Eli Lilly & Co.
   
5,674
     
6,102,217
 
Enliven Therapeutics, Inc. (b)
   
42,762
     
923,659
 
HUTCHMED China Ltd. - ADR (b)
   
43,441
     
626,419
 
Johnson & Johnson
   
12,777
     
2,643,817
 
Merck & Co., Inc.
   
20,974
     
2,198,704
 
Novartis AG
   
28,475
     
3,704,480
 
Nuvation Bio, Inc. – Class A (b)
   
238,898
     
1,918,351
 
Roche Holding AG - ADR
   
88,682
     
4,241,660
 
Terns Pharmaceuticals, Inc. (b)
   
14,967
     
420,722
 
             
31,600,919
 
TOTAL COMMON STOCKS (Cost $75,353,960)
     
104,115,765
 
                 
SHORT-TERM INVESTMENTS

 
MONEY MARKET FUNDS - 1.6%
 
Shares
   
Value
 
First American Treasury Obligations Fund - Class X, 3.91% (c)
   
1,672,347
     
1,672,347
 
TOTAL MONEY MARKET FUNDS (Cost $1,672,347)
     
1,672,347
 
                 
TOTAL INVESTMENTS - 100.2% (Cost $77,026,307)
     
105,788,112
 
Liabilities in Excess of Other Assets - (0.2)%
     
(234,797
)
TOTAL NET ASSETS - 100.0%
         
$
105,553,315
 

Percentages are stated as a percent of net assets.
 
 
The Global Industry Classification Standard (“GICS®”) was developed by and/or is the exclusive property of MSCI, Inc. (“MSCI”) and Standard & Poor’s Financial Services LLC (“S&P”). GICS® is a service mark of MSCI and S&P and has been licensed for use by U.S. Bank Global Fund Services.

ADR - American Depositary Receipt
PLC - Public Limited Company

(a)
To the extent that the Fund invests more heavily in particular industries or sectors of the economy, its performance will be especially sensitive to developments that significantly affect those industries or sectors.
(b)
Non-income producing security.
(c)
The rate shown represents the 7-day annualized yield as of November 30, 2025.

Tema ETF Trust
Tema Oncology ETF
Notes to Quarterly Schedule of Investments
November 30, 2025 (Unaudited)

Investment Valuation
The Fund discloses the fair value of their investments in a hierarchy that distinguishes between: (1) market participant assumptions developed based on market data obtained from sources independent of the Fund’s (observable inputs) and (2) the Fund’s own assumptions about market participant assumptions developed based on the best information available under the circumstances (unobservable inputs).

The three levels defined by the hierarchy are as follows:

• Level 1 — Quoted prices in active markets for identical assets that the Fund’s have the ability to access.
• Level 2 — Other significant observable inputs (including quoted prices for similar securities, interest rates, prepayment speeds, credit risk, etc.).
• Level 3 — Significant unobservable inputs (including the Fund’s own assumptions in determining the fair value of investments).

The inputs or methodology used for valuing securities are not necessarily an indication of the risk associated with investing in those securities.

The following is a summary of the inputs used to value the Fund’s investments as of November 30, 2025:


   
Level 1
   
Level 2
   
Level 3
   
Total
 
Assets
                       
Investments:
                       
  Common Stocks
 
$
104,115,765
   
$
–
   
$
–
   
$
104,115,765
 
  Money Market Funds
   
1,672,347
     
–
     
–
     
1,672,347
 
Total Investments
 
$
105,788,112
   
$
–
   
$
–
   
$
105,788,112
 
   
Refer to the Schedule of Investments for further disaggregation of investment categories.
 
   


Allocation of Portfolio Holdings by Country as of November 30, 2025
(% of Net Assets)

United States
 
$
83,192,430
     
78.9
%
Switzerland
   
7,946,140
     
7.5
 
United Kingdom
   
5,144,543
     
4.8
 
Denmark
   
3,988,726
     
3.8
 
Japan
   
2,073,563
     
1.9
 
China
   
1,683,612
     
1.6
 
Netherlands
   
1,132,679
     
1.1
 
Hong Kong
   
626,419
     
0.6
 
Liabilities in Excess of Other Assets
   
(234,797
)
   
(0.2
)
   
$
105,553,315
     
100.0
%


Sector Classification as of November 30, 2025
(% of Net Assets)

Health Care
 
$
104,115,765
     
98.6
%
Money Market Funds
   
1,672,347
     
1.6
 
Liabilities in Excess of Other Assets
   
(234,797
)
   
(0.2
)
   
$
105,553,315
     
100.0
%