<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0708</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001944095</cik>
        <entityName>MOAT BIOTECHNOLOGY Corp</entityName>
        <issuerAddress>
            <street1>5501 White Fences Road</street1>
            <city>OKLAHOMA CITY</city>
            <stateOrCountry>OK</stateOrCountry>
            <stateOrCountryDescription>OKLAHOMA</stateOrCountryDescription>
            <zipCode>73131</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>(405) 271-1469</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <previousName>MOAT Vaccine Technology Corporation</previousName>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Limited Liability Company</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2022</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Scott</firstName>
                <middleName>A.</middleName>
                <lastName>Rollins</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>5501 White Fences Road</street1>
                <city>Oklahoma City</city>
                <stateOrCountry>OK</stateOrCountry>
                <stateOrCountryDescription>OKLAHOMA</stateOrCountryDescription>
                <zipCode>73131</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Russell</firstName>
                <middleName>P.</middleName>
                <lastName>Rother</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>669 Meadowbrook Circle</street1>
                <city>Steamboat Springs</city>
                <stateOrCountry>CO</stateOrCountry>
                <stateOrCountryDescription>COLORADO</stateOrCountryDescription>
                <zipCode>80487</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Phillip</firstName>
                <lastName>Jones</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>1125 N. Porter Avenue, Suite 205</street1>
                <city>Norman</city>
                <stateOrCountry>OK</stateOrCountry>
                <stateOrCountryDescription>OKLAHOMA</stateOrCountryDescription>
                <zipCode>73071</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Todd</firstName>
                <lastName>Foley</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>2150 Rapid Creek Road</street1>
                <city>Alta</city>
                <stateOrCountry>WY</stateOrCountry>
                <stateOrCountryDescription>WYOMING</stateOrCountryDescription>
                <zipCode>83141</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Tetherex Pharmaceuticals</firstName>
                <lastName>Corporation</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>5501 White Fences Road</street1>
                <city>Oklahoma City</city>
                <stateOrCountry>OK</stateOrCountry>
                <stateOrCountryDescription>OKLAHOMA</stateOrCountryDescription>
                <zipCode>73131</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Michael</firstName>
                <lastName>Moradi-Araghi</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12 E. California, Suite 200</street1>
                <city>Oklahoma City</city>
                <stateOrCountry>OK</stateOrCountry>
                <stateOrCountryDescription>OKLAHOMA</stateOrCountryDescription>
                <zipCode>73104</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>No Revenues</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06b</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2025-10-03</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>26400</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>15593738</totalOfferingAmount>
            <totalAmountSold>26400</totalAmountSold>
            <totalRemaining>15567338</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>1</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
                <isEstimate>true</isEstimate>
            </salesCommissions>
            <findersFees>
                <dollarAmount>800000</dollarAmount>
                <isEstimate>true</isEstimate>
            </findersFees>
            <clarificationOfResponse>The Corporation has retained a finder who may receive finders' fees. The maximum expected finders' fee is $800,000.</clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>4500000</dollarAmount>
                <isEstimate>true</isEstimate>
            </grossProceedsUsed>
            <clarificationOfResponse>Tetherex provides employees &amp; certain services pursuant to that certain Administrative Services Agreement &amp; that certain Research Services Agreement, both by &amp; between Tetherex Pharmaceuticals Corporation &amp; MOAT Biotechnology Corporation, dated 9/6/2022</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>MOAT BIOTECHNOLOGY Corp</issuerName>
                <signatureName>Scott A. Rollins</signatureName>
                <nameOfSigner>Scott A. Rollins</nameOfSigner>
                <signatureTitle>CEO</signatureTitle>
                <signatureDate>2025-10-20</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
