144 0001567045 XXXXXXXX LIVE 0001937653 Zymeworks Inc. 001-41535 108 Patriot Drive Suite A Middletown DE 19709 302-274-8744 Galbraith, Kenneth Officer Director Common Stock Morgan Stanley

1585 Broadway New York NY 10036

23904 252427 70001987 01/05/2024 Nasdaq Common Stock 01/05/2024 Vesting of Restricted Stock Units Issuer N 47666 01/05/2024 Vesting of Award Y 01/05/2024 s/ Kenneth Galbraith