X0206 3 2023-04-10 0 0001937653 Zymeworks Inc. ZYME 0001971973 Miller Derek John Michael C/O ZYMEWORKS INC. 108 PATRIOT DRIVE, SUITE A MIDDLETOWN DE 19709 1 0 0 0 No securities are beneficially owned 0 D No securities are beneficially owned Not applicable 0 D Not applicable. Exhibit List - Exhibit 24 - Power of Attorney /s/ Daniel Dex, Attorney-in-Fact 2023-04-10