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Non-Cash Share-Based Compensation - Non-Cash Share-Based Compensation Expense (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2022
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Share-Based Compensation        
Share-based compensation expense   $ 71,963 $ 28,787 $ 193,556
Allocated from the Former Parent related to the Acceleration        
Share-Based Compensation        
Share-based compensation expense $ 101,440      
Research and development expenses        
Share-Based Compensation        
Share-based compensation expense   42,594 15,985 116,379
Research and development expenses | Allocated from the Former Parent excluding the Acceleration        
Share-Based Compensation        
Share-based compensation expense   0 0 46,976
Research and development expenses | Allocated from the Former Parent related to the Acceleration        
Share-Based Compensation        
Share-based compensation expense   0 0 61,749
Research and development expenses | 2022 Equity Incentive Plan        
Share-Based Compensation        
Share-based compensation expense   42,594 15,985 7,654
General and administrative expenses        
Share-Based Compensation        
Share-based compensation expense   29,369 12,802 77,177
General and administrative expenses | Allocated from the Former Parent excluding the Acceleration        
Share-Based Compensation        
Share-based compensation expense   0 0 30,951
General and administrative expenses | Allocated from the Former Parent related to the Acceleration        
Share-Based Compensation        
Share-based compensation expense   0 0 39,691
General and administrative expenses | 2022 Equity Incentive Plan        
Share-Based Compensation        
Share-based compensation expense   $ 29,369 $ 12,802 $ 6,535