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Shareholders' Equity (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended 15 Months Ended
Oct. 02, 2024
USD ($)
$ / shares
shares
Apr. 22, 2024
USD ($)
$ / shares
shares
Jan. 07, 2024
USD ($)
shares
Oct. 05, 2023
USD ($)
$ / shares
shares
Oct. 03, 2022
shares
Dec. 31, 2024
USD ($)
shares
May 31, 2024
USD ($)
shares
Dec. 31, 2023
USD ($)
shares
Oct. 31, 2022
$ / shares
shares
Mar. 31, 2024
USD ($)
shares
Dec. 31, 2024
USD ($)
shares
Dec. 31, 2024
USD ($)
shares
Dec. 31, 2023
USD ($)
shares
Dec. 31, 2022
USD ($)
shares
Dec. 31, 2024
USD ($)
shares
Aug. 31, 2024
USD ($)
May 01, 2024
USD ($)
$ / shares
shares
Oct. 31, 2023
USD ($)
Sale of Stock [Line Items]                                    
Obligation to issue common shares as payment under license and other agreements | $                       $ 8,554            
Common stock issued (shares)               721,136                    
Issuance of common shares, net of offering costs | $               $ 21,814       $ 664,015 $ 242,425 $ 282,804        
Shares converted due to spinoff (in shares)         0.5                          
Shares issued in spinoff (in shares)         35,840,459                          
Pyramid                                    
Sale of Stock [Line Items]                                    
Upfront payment of common shares, shares (in shares)     255,794,000                              
Upfront payment of common shares, value | $     $ 10,894                              
Upfront payment of common shares, shares issued (in shares)                     253,838,000              
R&D expense | $                   $ 5,689                
Common shares issuable (in shares)                   98,129                
Common shares issued (in shares)                       97,387            
Purchase Agreement, Knopp Amendment                                    
Sale of Stock [Line Items]                                    
Number of securities called by warrants (shares)                                 294,195  
Exercise price of warrants (in dollars per share) | $ / shares                                 $ 67.98  
Warrants, fair value disclosure | $                                 $ 3,340  
Purchase Agreement, Knopp Amendment                                    
Sale of Stock [Line Items]                                    
Common stock issued (shares)             1,872,874                      
Issuance of common shares, net of offering costs | $             $ 65,981                      
FGFR3 Agreement, GeneQuantum Healthcare Co. Ltd. and Aimed Bio, Inc.                                    
Sale of Stock [Line Items]                                    
Obligation to issue common shares as payment under license and other agreements (in shares)           222,119                        
Obligation to issue common shares as payment under license and other agreements | $           $ 8,554                        
Common Shares                                    
Sale of Stock [Line Items]                                    
Common stock issued (shares)                       16,752,439 11,761,363 28,750,000        
Issuance of common shares, net of offering costs | $                       $ 664,015 $ 242,425 $ 282,804        
Number of shares sold in transaction (in shares) 6,052,631 6,451,220                                
Issuance price per share (in dollars per share) | $ / shares $ 47.50 $ 41.00                                
Proceeds from sale of stock | $ $ 269,935 $ 247,830                                
Equity distribution agreement aggregate amount | $           $ 300,000         $ 300,000 $ 300,000     $ 300,000 $ 450,000   $ 150,000
Shares issued in spinoff (in shares)                           39,375,944        
Issuance of common shares under 2022 Equity Incentive Plan (in shares)                           64,535        
IPO                                    
Sale of Stock [Line Items]                                    
Number of shares sold in transaction (in shares)                 25,000,000                  
Issuance price per share (in dollars per share) | $ / shares                 $ 10.50                  
Over-allotment option                                    
Sale of Stock [Line Items]                                    
Number of shares sold in transaction (in shares)                 3,750,000                  
Public offering                                    
Sale of Stock [Line Items]                                    
Common stock issued (shares)       11,761,363                            
Issuance of common shares, net of offering costs | $       $ 242,425                            
Exercise price per share in dollars per share) | $ / shares       $ 22.00                            
Equity Distribution Agreement | Common Shares                                    
Sale of Stock [Line Items]                                    
Common stock issued (shares)                             4,248,588      
Proceeds from sale of stock | $                             $ 146,250      
Restricted Share Units | Legacy Plan                                    
Sale of Stock [Line Items]                                    
Issuance of common shares under 2022 Equity Incentive Plan (in shares)         924,093                          
Former Parent Stock Options | Legacy Plan                                    
Sale of Stock [Line Items]                                    
Issuance of common shares under 2022 Equity Incentive Plan (in shares)         2,611,392