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License, Acquisitions and Other Agreements - ALS Biopharma Agreement (Details)
1 Months Ended 3 Months Ended 6 Months Ended
Aug. 31, 2015
prodrug
claim
Jun. 30, 2024
USD ($)
Jun. 30, 2023
USD ($)
Jun. 30, 2024
USD ($)
Jun. 30, 2023
USD ($)
License and other agreements          
Milestone payment to be paid upon regulatory achievement   $ 641,975,000   $ 641,975,000  
Research and development   314,819,000 $ 79,490,000 470,791,000 $ 142,951,000
ALS Biopharma Agreement | Collaborative arrangement          
License and other agreements          
Number of prodrugs of glutamate modulating agents | prodrug 300        
Milestone payment to be paid upon regulatory achievement   4,000,000   4,000,000  
Number of claims | claim 1        
Research and development   $ 0 $ 0 $ 0 $ 0