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Commitments and Contingencies - Narrative (Details)
12 Months Ended
Jun. 30, 2022
USD ($)
Jan. 01, 2021
USD ($)
shares
Dec. 31, 2023
USD ($)
term
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Other Commitments [Line Items]          
Operating lease cost     $ 5,874,000 $ 1,158,000 $ 264,000
Operating cash flows paid for operating leases     $ 4,854,000 780,000  
Number of additional periods | term     2    
Annual commitments     $ 39,780,000    
Research and development     373,281,000 437,072,000 181,486,000
Moda Pharmaceuticals LLC          
Other Commitments [Line Items]          
Research and development     $ 0 $ 0 $ 0
Moda Pharmaceuticals LLC | Moda Agreement          
Other Commitments [Line Items]          
Eligible development milestone payments   $ 81,612,000      
Eligible commercial milestone payments   $ 30,171,000      
Initial term of agreement (in years)   4 years      
Moda Pharmaceuticals LLC | License agreement | Moda Agreement          
Other Commitments [Line Items]          
Payment for license agreement   $ 2,700,000      
Issuance of common shares as payment for assets (in shares) | shares   37,836      
Issuance of common shares as payment for assets   $ 3,243,000      
West Palm Beach Lease Agreement          
Other Commitments [Line Items]          
Lease agreement, term 120 months        
Option to extend, term 60 months        
Minimum          
Other Commitments [Line Items]          
Lease agreement, term     1 year    
Option to extend, term     5 years    
Minimum | West Palm Beach Lease Agreement          
Other Commitments [Line Items]          
Annual commitments $ 1,263,000        
Maximum          
Other Commitments [Line Items]          
Lease agreement, term     10 years    
Option to extend, term     10 years    
Maximum | West Palm Beach Lease Agreement          
Other Commitments [Line Items]          
Annual commitments $ 1,649,000        
Research and Development Arrangement          
Other Commitments [Line Items]          
Research commitments     $ 9,025,000    
Research commitment period     1 year