Commitments and Contingencies - Narrative (Details) - USD ($)		3 Months Ended		9 Months Ended
	Jan. 01, 2021	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022
Liability For Sale of Future Royalties [Line Items]
Eligible development milestone payments		$ 1,325,000		$ 1,325,000
Research and development		95,517,000	$ 52,845,000	238,468,000	$ 300,028,000
Moda Pharmaceuticals LLC | Moda Agreement
Liability For Sale of Future Royalties [Line Items]
Eligible development milestone payments	$ 81,612,000
Eligible commercial milestone payments	$ 30,171,000
Initial term of agreement (in years)	4 years
Moda Pharmaceuticals LLC | License agreement | Moda Agreement
Liability For Sale of Future Royalties [Line Items]
Payment for license agreement	$ 2,700,000
Issuance of common shares as payment for assets (in shares)	37,836
Issuance of common shares as payment for assets	$ 3,243,000
Artizan Biosciences Inc
Liability For Sale of Future Royalties [Line Items]
Research and development		$ 0	$ 0	0	$ 0
Research and Development Arrangement
Liability For Sale of Future Royalties [Line Items]
Research commitments				$ 11,475,000
Research commitment period				2 years