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License Agreements - UCONN (Details) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
License and other agreements          
Commercial milestone payment to be paid   $ 1,270,450,000   $ 1,270,450,000  
Research and development   95,517,000 $ 52,845,000 238,468,000 $ 300,028,000
UCONN          
License and other agreements          
Research and development   $ 0 0 $ 0 0
UCONN Agreement | UCONN          
License and other agreements          
Milestone payment to be paid upon developmental and regulatory achievement $ 30,100,000        
Commercial milestone payment to be paid 50,000,000   $ 50,000,000   $ 50,000,000
UCONN Agreement | UCONN | License agreement          
License and other agreements          
Payment for license agreement $ 400,000