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License Agreements - Moda Pharmaceuticals LLC (Details) - USD ($)
3 Months Ended 6 Months Ended
Jan. 01, 2021
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
License and other agreements          
Research and development   $ 79,490,000 $ 177,087,000 $ 142,951,000 $ 247,183,000
Moda Pharmaceuticals LLC          
License and other agreements          
Research and development   $ 0 $ 0 $ 0 $ 0
Moda Pharmaceuticals LLC | Moda Agreement          
License and other agreements          
Eligible development milestone payments $ 81,612,000        
Eligible commercial milestone payments $ 30,171,000        
Initial term of agreement (in years) 4 years        
Moda Pharmaceuticals LLC | Moda Agreement | License agreement          
License and other agreements          
Payment for license agreement $ 2,700,000        
Issuance of common shares as payment for assets (in shares) 37,836        
Issuance of common shares as payment for assets $ 3,243,000