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License Agreements - Fox Chase Chemical Diversity Center Agreement (Details) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
May 31, 2019
Jun. 30, 2023
Dec. 31, 2022
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Nov. 30, 2020
License and other agreements              
Development milestone payment to be paid   $ 125,050,000     $ 125,050,000    
Research and development   79,490,000   $ 177,087,000 142,951,000 $ 247,183,000  
FCCDC Agreement              
License and other agreements              
Research and development   $ 0   $ 0 $ 0 $ 0  
FCCDC Agreement | Collaborative arrangement              
License and other agreements              
Common stock issued (shares) 100,000            
Issuance of common shares, net of offering costs $ 5,646,000            
Development milestone payment to be paid 3,000,000            
Development milestone payments to be paid per each additional NDA filing $ 1,000,000            
FCCDC Agreement | Collaborative arrangement | Minimum              
License and other agreements              
Earned royalty payment per agreement (percent)             0.00%
FCCDC Agreement | Collaborative arrangement | Maximum              
License and other agreements              
Earned royalty payment per agreement (percent)             10.00%
FCCDC Warrants              
License and other agreements              
Number of securities called by warrants (shares) 100,000            
Exercise price of warrants (in dollars per share) $ 56.46            
Research and development     $ 4,245,000