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License Agreements - Taldefgrobep Alfa License Agreement (Details) - USD ($)
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Feb. 28, 2022
License and other agreements      
Research and development $ 63,461,000 $ 70,096,000  
BMS      
License and other agreements      
Research and development $ 0 $ 0  
BMS | Taldefgrobep Alfa License Agreement      
License and other agreements      
Eligible milestone payment per agreement upon specified performance and regulatory milestones     $ 200,000,000