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License Agreements - UCONN (Details) - USD ($)
1 Months Ended 3 Months Ended
Sep. 30, 2022
Mar. 31, 2023
Mar. 31, 2022
License and other agreements      
Commercial milestone payment to be paid   $ 1,420,450,000  
Research and development   63,461,000 $ 70,096,000
UCONN      
License and other agreements      
Research and development   $ 0 $ 0
UCONN Agreement | UCONN      
License and other agreements      
Milestone payment to be paid upon developmental and regulatory achievement $ 30,100,000    
Commercial milestone payment to be paid 50,000,000    
UCONN Agreement | UCONN | License agreement      
License and other agreements      
Payment for license agreement $ 400,000