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Related Party Transactions - Net Transfers from Parent (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Sep. 30, 2022
Sep. 30, 2021
Related Party Transactions                
Net transfers from Former Parent as reflected in the Combined Statement of Cash Flows             $ 237,417 $ 390,437
Net transfers from Former Parent as reflected in the Combined Statement of Changes in Equity $ 144,071 $ 182,186 $ 108,440 $ 333,743 $ 39,682 $ 93,214    
Former Parent                
Related Party Transactions                
Net transfers from Former Parent as reflected in the Combined Statement of Cash Flows             237,417 390,437
Net transfers from Former Parent as reflected in the Combined Statement of Changes in Equity             434,697 466,639
Former Parent | General financing activities                
Related Party Transactions                
Net transfers from Former Parent as reflected in the Combined Statement of Cash Flows             187,519 365,360
Former Parent | Corporate cost allocations, excluding share-based compensation                
Related Party Transactions                
Net transfers from Former Parent as reflected in the Combined Statement of Cash Flows             49,898 25,077
Former Parent | Share-based compensation                
Related Party Transactions                
Net transfers from Former Parent as reflected in the Combined Statement of Changes in Equity             77,927 52,671
Former Parent | Issuance of Former Parent common shares to repurchase non-controlling interest in a subsidiary                
Related Party Transactions                
Net transfers from Former Parent as reflected in the Combined Statement of Changes in Equity             60,000 0
Former Parent | Issuance of Former Parent common shares as payment for IPR&D asset acquisition                
Related Party Transactions                
Net transfers from Former Parent as reflected in the Combined Statement of Changes in Equity             58,747 0
Former Parent | Issuance of Former Parent common shares as payment for business acquisition                
Related Party Transactions                
Net transfers from Former Parent as reflected in the Combined Statement of Changes in Equity             0 10,673
Former Parent | Issuance of Former Parent common shares as payment for Artizan investment                
Related Party Transactions                
Net transfers from Former Parent as reflected in the Combined Statement of Changes in Equity             0 6,000
Former Parent | Issuance of Former Parent common shares as payment for license and consulting agreements                
Related Party Transactions                
Net transfers from Former Parent as reflected in the Combined Statement of Changes in Equity             1,779 7,929
Former Parent | Other non-cash adjustments                
Related Party Transactions                
Net transfers from Former Parent as reflected in the Combined Statement of Changes in Equity             $ (1,173) $ (1,071)