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License Agreements - AstraZeneca License Agreement (Details) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
Sep. 30, 2018
Oct. 31, 2016
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
License and other agreements            
Research and development     $ 52,845,000 $ 46,973,000 $ 300,028,000 $ 139,668,000
AstraZeneca            
License and other agreements            
Research and development     0 0 0 0
AstraZeneca | Collaborative arrangement            
License and other agreements            
Research and development     $ 0 $ 0 $ 0 $ 0
AstraZeneca | Collaborative arrangement | Maximum            
License and other agreements            
Milestone payment to be paid upon regulatory achievement   $ 30,000,000        
Milestone payment to be paid for any product other than rimegepant   60,000,000        
Commercial milestone payment to be paid   $ 120,000,000        
Agreement term after first commercial sale   10 years        
Royalty Payment To Be Paid By Company Upon Specified Approved Products By Net Sales, Percentage 10.00%          
AstraZeneca | Collaborative arrangement | Minimum            
License and other agreements            
Royalty Payment To Be Paid By Company Upon Specified Approved Products By Net Sales, Percentage 0.00%          
AstraZeneca | License agreement            
License and other agreements            
Payment for license agreement $ 3,000,000          
Issuance of common shares as payment for assets (in shares) 109,523          
Issuance of common shares as payment for assets $ 4,080,000          
Milestone payment due upon achievement of specified regulatory and commercial milestones 55,000,000          
Milestone payment due upon achievement of specified sales-based milestones $ 50,000,000          
AstraZeneca | License agreement | Maximum            
License and other agreements            
Royalty Payment To Be Paid By Company Upon Specified Approved Products By Net Sales, Percentage 10.00%          
AstraZeneca | License agreement | Minimum            
License and other agreements            
Royalty Payment To Be Paid By Company Upon Specified Approved Products By Net Sales, Percentage 0.00%