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License Agreements - ALS Biopharma Agreement (Details)
1 Months Ended 3 Months Ended 9 Months Ended
Aug. 31, 2015
USD ($)
prodrug
claim
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
License and other agreements          
Research and development   $ 52,845,000 $ 46,973,000 $ 300,028,000 $ 139,668,000
ALS Biopharma Agreement | Collaborative arrangement          
License and other agreements          
Number of prodrugs of glutamate modulating agents | prodrug 300        
Milestone payment to be paid upon regulatory achievement $ 3,000,000        
Milestone payment to be paid for subsequently developed products $ 1,000,000        
Number of claims | claim 1        
Research and development   $ 0 $ 0 $ 0 $ 0