License Agreements - Yale University Agreement (Details) - USD ($)	1 Months Ended		3 Months Ended		9 Months Ended
	Jan. 31, 2021	May 31, 2019	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
License and other agreements
Research and development			$ 52,845,000	$ 46,973,000	$ 300,028,000	$ 139,668,000
Yale University | Yale Arrangement
License and other agreements
Milestone payment to be paid upon regulatory achievement		$ 2,000,000
Minimum annual royalty payment to be paid upon sale of product		$ 1,000,000
Research and development			0	0	0	0
Yale University | Yale MoDE Agreement
License and other agreements
Minimum annual royalty payment to be paid upon sale of product	$ 1,000,000
Eligible development milestone payments	800,000
Eligible commercial milestone payments	$ 2,950,000
Initial term of agreement (in years)	20 years
Amount of funding	$ 4,000,000
Research and development			$ 333,000	$ 0	$ 2,333,000	$ 150,000
Yale University | Yale MoDE Agreement | License agreement
License and other agreements
Payment for license agreement	$ 1,000,000
Issuance of common shares as payment for assets (in shares)	11,668
Issuance of common shares as payment for assets	$ 1,000,000