X0206 3 2022-05-16 0 0001781983 Aprea Therapeutics, Inc. APRE 0001925150 Duey Marc 535 BOYLSTON STREET BOSTON MA 02116 true Common Stock 151904 D Common Stock 439 I By spouse Stock Option (right to buy) 0.44 2022-05-16 2028-05-30 Common Stock 51154 D Series A Non-Voting Convertible Preferred Stock Common Stock 400969 D Series A Non-Voting Convertible Preferred Stock Common Stock 1161 I By spouse Following stockholder approval at the Issuer's annual stockholder's meeting, each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of the Issuer's common stock ("Common Stock") at any time at the option of the holder thereof, subject to certain limitations, including that a holder of Series A Non-Voting Convertible Preferred Stock is prohibited from converting shares of Series A Non-Voting Convertible Preferred Stock into shares of Common Stock if, as a result of such conversion, such holder, together with its affiliates, would beneficially own more than a specified percentage (to be established by the holder between 4.9% and 19.9%) of the total number of shares of Common Stock issued and outstanding immediately after giving effect to such conversion. The Series A Non-Voting Convertible Preferred Stock has no expiration date. Exhibit 24 - Power of Attorney /s/ Scott M. Coiante, attorney-in-fact 2022-05-26