<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns0="http://www.sec.gov/edgar/common">
<headerData>
<submissionType>144</submissionType>
<filerInfo>
<filer>
<filerCredentials>
<cik>0001951275</cik>
<ccc>XXXXXXXX</ccc>
</filerCredentials>
</filer>
<liveTestFlag>LIVE</liveTestFlag>
</filerInfo>
</headerData>
<formData>
<issuerInfo>
<issuerCik>0001921865</issuerCik>
<issuerName>ASP Isotopes Inc.</issuerName>
<secFileNumber>001-41555</secFileNumber>
<issuerAddress>
<ns0:street1>2200 Ross Avenue</ns0:street1>
<ns0:street2>Suite 4575E</ns0:street2>
<ns0:city>Dallas</ns0:city>
<ns0:stateOrCountry>TX</ns0:stateOrCountry>
<ns0:zipCode>75201</ns0:zipCode>
</issuerAddress>
<issuerContactPhone>(214) 4328219</issuerContactPhone>
<nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Ainscow Robert</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
<relationshipsToIssuer>
<relationshipToIssuer>OFFICER</relationshipToIssuer>
</relationshipsToIssuer>
</issuerInfo>
<securitiesInformation>
<securitiesClassTitle>Common Stock</securitiesClassTitle>
<brokerOrMarketmakerDetails>
<name>Independent Trading Group (ITG) Inc.</name>
<address>
<ns0:street1>33 Yonge Street </ns0:street1>
<ns0:street2>Suite 420</ns0:street2>
<ns0:city>Toronto</ns0:city>
<ns0:stateOrCountry>A6</ns0:stateOrCountry>
<ns0:zipCode>M5E 1G4</ns0:zipCode>
</address>
</brokerOrMarketmakerDetails>
<noOfUnitsSold>22500</noOfUnitsSold>
<aggregateMarketValue>121050.00</aggregateMarketValue>
<noOfUnitsOutstanding>125903447</noOfUnitsOutstanding>
<approxSaleDate>04/16/2026</approxSaleDate>
<securitiesExchangeName>NASDAQ</securitiesExchangeName>
</securitiesInformation>
<securitiesToBeSold>
<securitiesClassTitle>Common Stock</securitiesClassTitle>
<acquiredDate>04/14/2025</acquiredDate>
<natureOfAcquisitionTransaction>Acquired as compensation --Restricted Stock Award</natureOfAcquisitionTransaction>
<nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
<isGiftTransaction>N</isGiftTransaction>
<amountOfSecuritiesAcquired>400000</amountOfSecuritiesAcquired>
<paymentDate>04/14/2025</paymentDate>
<natureOfPayment>Equity Compensation</natureOfPayment>
</securitiesToBeSold>
<nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
<securitiesSoldInPast3Months>
<sellerDetails>
<name>Ainscow Robert</name>
<address>
<ns0:street1>c/o ASP Isotopes Inc.</ns0:street1>
<ns0:street2>2200 Ross Avenue, Suite 4575E</ns0:street2>
<ns0:city>Dallas</ns0:city>
<ns0:stateOrCountry>TX</ns0:stateOrCountry>
<ns0:zipCode>75201</ns0:zipCode>
</address>
</sellerDetails>
<securitiesClassTitle>Common Stock</securitiesClassTitle>
<saleDate>03/06/2026</saleDate>
<amountOfSecuritiesSold>8438</amountOfSecuritiesSold>
<grossProceeds>45894.28</grossProceeds>
</securitiesSoldInPast3Months>
<securitiesSoldInPast3Months>
<sellerDetails>
<name>Ainscow Robert</name>
<address>
<ns0:street1>c/o ASP Isotopes Inc.</ns0:street1>
<ns0:street2>2200 Ross Avenue, Suite 4575E</ns0:street2>
<ns0:city>Dallas</ns0:city>
<ns0:stateOrCountry>TX</ns0:stateOrCountry>
<ns0:zipCode>75201</ns0:zipCode>
</address>
</sellerDetails>
<securitiesClassTitle>Common Stock</securitiesClassTitle>
<saleDate>04/13/2026</saleDate>
<amountOfSecuritiesSold>25000</amountOfSecuritiesSold>
<grossProceeds>112775.00</grossProceeds>
</securitiesSoldInPast3Months>
<remarks>The sale of shares reported in this Form 144 is expected to be sold on the date indicated pursuant to a Rule 10b5-1 trading plan and includes an amount for the purpose of satisfying the Reporting Person's income tax liabilities resulting from the quarterly vesting of a previously granted restricted stock award for 400,000 shares pursuant to an issuer equity incentive plan.  The Aggregate Market Value of the shares to be sold is based on the closing market price of $5.38 on April 15, 2026.</remarks>
<noticeSignature>
<noticeDate>04/16/2026</noticeDate>
<planAdoptionDates>
<planAdoptionDate>06/09/2025</planAdoptionDate>
</planAdoptionDates>
<signature>/s/ Robert Ainscow</signature>
</noticeSignature>
</formData>
</edgarSubmission>
