144 0001918845 XXXXXXXX LIVE 0001534120 AVALO THERAPEUTICS INC 001-37590 1500 Liberty Ridge Drive, Suite 321 Wayne PA 19087 4105228707 MITTIE DOYLE Officer Common Morgan Stanley Smith Barney LLC Executive Financial Services

1 New York Plaza 8th Floor New York NY 10004

65800 1168608.00 22788452 04/06/2026 NASDAQ Common 04/06/2026 Exercise of Stock Options Issuer N 65800 04/06/2026 Cash N 10b5-1 Sales for MITTIE DOYLE

1500 Liberty Ridge Drive, Suite 321 Wayne PA 19087

Common 04/01/2026 679 10864.00 10b5-1 Sales for MITTIE DOYLE

1500 Liberty Ridge Drive, Suite 321 Wayne PA 19087

Common 03/16/2026 25492 411606.58 The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale. 04/06/2026 11/13/2025 /s/ Mittie Doyle