X0508 4 2025-08-15 0000842023 BIO-TECHNE Corp TECH 0001908268 McManus Matthew 614 MCKINLEY PLACE NE MINNEAPOLIS MN 55413 0 1 0 0 President - Diag & Spatial Bio 0 Common Stock 2025-08-15 4 M 0 2637 0 A 5615 D Common Stock 2025-08-15 4 F 0 880 53.60 D 4735 D Performance Restricted Stock Units Common Stock 2888 2888 D Performance Stock Option (Right to Buy) 68.54 2031-02-01 Common Stock 7951 7951 D Restricted Stock Units Common Stock 9241 9241 D Stock Option (Right to Buy) 68.54 2031-02-01 Common Stock 15902 15902 D Performance Restricted Stock Units Common Stock 15825 15825 D Restricted Stock Units 2025-08-15 4 M 0 2637 0 D Common Stock 2637 5275 D Stock Option (Right to Buy) 74.91 2034-08-15 Common Stock 21320 21320 D Performance Restricted Stock Units 2025-08-15 4 A 0 19243 0 A Common Stock 19243 19243 D Restricted Stock Units 2025-08-15 4 A 0 9622 0 A Common Stock 9622 9622 D Stock Option (Right to Buy) 53.60 2025-08-15 4 A 0 24614 0 A 2035-08-15 Common Stock 24614 24614 D Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock. Vests in full or in part on 8/15/2026 if certain performance goals are achieved (or such later date as performance is certified by the Administrator). 4,620 restricted stock units vest on 2/1/2025 and 2/1/2027, and 4,621 restricted stock units vest on 2/1/2026. Options to purchase 3,976 shares vest on 2/1/2025 and 2/1/2027, and options to purchase 3,975 shares vest on 2/1/2026 and 2/1/2028. Vests in full or in part on 8/15/2027 if certain performance goals are achieved (or such later date as performance is certified by the Administrator). 2,637 restricted stock units vest on each of 8/15/2025 and 8/15/2026, and 2,638 restricted stock units vest on 8/15/2027. Options to purchase 5,330 shares vest on each of 8/15/2025, 8/15/2026, 8/15/2027 and 8/15/2028. Vests in full or in part on 8/15/2028 if certain performance goals are achieved (or such later date as performance is certified by the Administrator). 3,207 restricted stock units vest on each of 8/15/2026 and 8/15/2027, and 3,208 restricted stock units vest on 8/15/2028. Options to purchase 8,205 shares vest on each of 8/15/2026 and 8/15/2027, and options to purchase 8,204 shares vest on 8/15/2028. /s/ Andrew Nick as Attorney-in-Fact for Matthew McManus pursuant to Power of Attorney previously filed. 2025-08-19