Basis of Presentation and Summary of Significant Accounting Policies - Narrative (Details) - USD ($)					3 Months Ended		6 Months Ended
	Aug. 07, 2023	Jul. 20, 2023	Jul. 13, 2023	Apr. 13, 2023	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022	Feb. 13, 2023	Dec. 31, 2022	Jun. 16, 2022
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Research and development					$ 9,548,000	$ 7,456,000	$ 20,463,000	$ 14,260,000
Debt Instrument [Line Items]
Accumulated deficit					427,303,000		427,303,000			$ 376,797,000
Net loss					25,898,000	13,349,000	50,506,000	25,266,000
Net cash outflows from operations							29,044,000	21,499,000
Cash					7,514,000		7,514,000			$ 7,065,000
Working capital deficit					$ 20,800,000		$ 20,800,000
ELOC, right to sell common stock (in shares)									$ 35,000,000		$ 150,000,000
Common stock, par value (in usd per share)					$ 0.0001		$ 0.0001			$ 0.0001	$ 0.0001
ELOC, ownership restriction percentage											9.90%
ELOC, floor stock price (in usd per share)											$ 1.00
Proceeds from stock issuance							$ 15,700,000
Issuance of stock (in shares)							13,239,654
Proceeds from Term Loan							$ 14,357,000	19,870,000
Unrealized losses on Term Loan					$ 345,000	0	345,000	0
Marketable investments					$ 1,200,000		$ 1,200,000			$ 1,200,000
Warrants, quoted price (in usd per share)					$ 0.19		$ 0.19
Warrants outstanding (in shares)					17,916,609		17,916,609
SR&ED investment tax credit					$ 0	400,000	$ 0	800,000
Subsequent Event
Debt Instrument [Line Items]
ELOC, right to sell common stock (in shares)			$ 35,000,000
Proceeds from stock issuance	$ 34,200,000
Issuance of stock (in shares)	16,590,877
Revision of Prior Period, Error Correction, Adjustment
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Research and development					400,000		700,000
Interest expense						$ 300,000		$ 300,000
Term Loan | Line of credit
Debt Instrument [Line Items]
Face amount				$ 50,000,000.0
Non-dilutive financing				$ 25,000,000.0
Premium payment, percentage of amount prepaid from common stock issuance proceeds				10.00%
Unrealized losses on Term Loan					$ 300,000		$ 300,000
Term Loan | Line of credit | Subsequent Event
Debt Instrument [Line Items]
Premium payment, percentage of amount prepaid from common stock issuance proceeds		10.00%
Term Loan | Line of credit | Debt tranche one
Debt Instrument [Line Items]
Face amount				$ 15,000,000.0
Term Loan | Line of credit | Debt tranche two
Debt Instrument [Line Items]
Face amount				15,000,000
Term Loan | Line of credit | Debt tranche two | Subsequent Event
Debt Instrument [Line Items]
Proceeds from Term Loan			$ 15,000,000
Term Loan | Line of credit | Debt tranche three
Debt Instrument [Line Items]
Face amount				$ 20,000,000.0