Income taxes - Reconciliation of Effective Tax Rate (Details)	12 Months Ended
Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Income Tax Disclosure [Abstract]
US federal tax rate	21.00%	27.00%	27.00%
State tax	1.00%	0.00%	0.00%
Foreign losses taxed at different rates	5.00%	0.00%	1.00%
Return to provision adjustments	(1.00%)	0.00%	0.00%
Stock-based compensation	(3.00%)	0.00%	0.00%
Research and development credits	5.00%	0.00%	(3.00%)
Permanent differences	(24.00%)	(2.00%)	18.00%
Other	0.00%	1.00%	7.00%
Change in valuation allowance	(4.00%)	(26.00%)	(50.00%)
Effective tax rate	0.00%	0.00%	0.00%

Effective Income Tax Rate Reconciliation, Permanent Differences, Percent

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Percentage of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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Percentage of domestic federal statutory tax rate applicable to pretax income (loss).

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to changes in the valuation allowance for deferred tax assets.

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations applicable to statutory income tax expense (benefit) outside of the country of domicile.

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to revisions of previously reported income tax expense.

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Percentage of difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying domestic federal statutory income tax rate to pretax income (loss) from continuing operation, attributable to expense for award under share-based payment arrangement. Excludes expense determined to be nondeductible upon grant or after for award under share-based payment arrangement.

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations applicable to state and local income tax expense (benefit), net of federal tax expense (benefit).

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