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Leases (Tables)
 12 Months Ended
Dec. 31, 2022
Leases [Abstract]  
Lease costs and other information The lease costs are reflected in the statement of operations and comprehensive loss as follows (in thousands):
December 31,
202220212020
Research and development$224 $268 $268 
General and administrative1,542 1,347 1,398 
Less: sublease income(260)(260)(42)
Total lease costs$1,506 $1,355 $1,624 


The weighted-average remaining lease terms and discount rates for operating leases were as follows:
December 31,
202220212020
Weighted average remaining lease term in years2.82.92.4
Weighted average discount rate (1)17 %18 %20 %

(1) For the lease contracts denominated in Canadian dollars, the discount rate was determined on a currency-equivalent basis.
Future minimum operating lease payments
Future minimum operating lease payment under non-cancelable leases as of December 31, 2022, were as follows (in thousands):

Year ended December 31,Operating leases
2023$1,533 
20241,341 
20251,137 
20261,168 
20271,199 
Thereafter7,849 
Total future minimum lease payments$14,227