The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ALLOGENE THERAPEUTICS INC COM 019770106 BBG00KHRRDY2 2,493,218 396,378 SH   SOLE   396,378 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 BBG001SD42R0 11,667,110 9,642,240 SH   SOLE   9,642,240 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 BBG007KGRPZ3 15,513,000 300,000 SH   SOLE   300,000 0 0
BURNING ROCK BIOTECH LTD SPONSORED ADS 12233L107 BBG00V1JWFQ1 16,631,057 7,391,581 SH   SOLE   7,391,581 0 0
CABALETTA BIO INC COM 12674W109 BBG00MJ3BKX1 1,530,746 165,486 SH   SOLE   165,486 0 0
CATALYST BIOSCIENCES INC COM NEW 14888D208 BBG001SDL5X7 47,730 90,484 SH   SOLE   90,484 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 BBG001S7QN20 71,552,232 1,605,390 SH   SOLE   1,605,390 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100 BBG01081FC68 2,275,171 733,926 SH   SOLE   733,926 0 0
COGENT BIOSCIENCES INC COM 19240Q201 BBG007DHY102 9,179,206 794,049 SH   SOLE   794,049 0 0
CONCERT PHARMACEUTICALS INC COM 206022105 BBG001V2MTD6 25,814,838 4,420,349 SH   SOLE   4,420,349 0 0
CONNECT BIOPHARMA HLDGS LTD ADS 207523101 BBG00ZGYNJZ5 641,867 739,649 SH   SOLE   739,649 0 0
GOSSAMER BIO INC COM 38341P102 BBG00MVWLMC1 3,844,253 1,771,545 SH   SOLE   1,771,545 0 0
GSK PLC SPONSORED ADR 37733W204 BBG001SD6SM6 17,627,735 501,643 SH   SOLE   501,643 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 BBG001T9M4T2 125,180,000 1,100,000 SH   SOLE   1,100,000 0 0
LIQUIDIA CORPORATION COM NEW 53635D202 BBG001V0GFD7 11,165,597 1,752,841 SH   SOLE   1,752,841 0 0
MIRATI THERAPEUTICS INC COM 60468T105 BBG001SF6HK7 8,661,369 191,158 SH   SOLE   191,158 0 0
NATERA INC COM 632307104 BBG001V0FSF8 104,570,825 2,603,207 SH   SOLE   2,603,207 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 BBG005Y0QF99 61,469 120,764 SH   SOLE   120,764 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106 BBG00T5JMRV1 4,961,823 2,025,234 SH   SOLE   2,025,234 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 BBG002B63KP4 5,683,259 520,922 SH   SOLE   520,922 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 BBG001TFZB81 2,375,606 561,609 SH   SOLE   561,609 0 0
SERES THERAPEUTICS INC COM 81750R102 BBG0099X6868 4,349,307 776,662 SH   SOLE   776,662 0 0
SUTRO BIOPHARMA INC COM 869367102 BBG001T94MP6 3,268,716 404,544 SH   SOLE   404,544 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 BBG001T92272 65,182,209 2,561,187 SH   SOLE   2,561,187 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 BBG001SL72C5 8,792,622 418,099 SH   SOLE   418,099 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 BBG001S8RV10 27,809,000 100,000 SH   SOLE   100,000 0 0
VAXCYTE INC COM 92243G108 BBG009PHHPP4 33,729,996 703,441 SH   SOLE   703,441 0 0
VERA THERAPEUTICS INC CL A 92337R101 BBG00Q72WYH2 27,266,046 1,409,098 SH   SOLE   1,409,098 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 BBG002H24301 30,223,499 1,034,697 SH   SOLE   1,034,697 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 BBG00B642V63 8,667,274 1,238,182 SH   SOLE   1,238,182 0 0
XENON PHARMACEUTICALS INC COM 98420N105 BBG002VBMLS5 1,139,014 28,887 SH   SOLE   28,887 0 0