X0206 3 2022-05-19 0 0001907685 Comera Life Sciences Holdings, Inc. CMRA 0001448698 Cherington Charles C/O ARA PARTNERS 5300 MEMORIAL DRIVE, SUITE 500 HOUSTON TX 77077 0 0 1 0 Common Stock 575030 D Common Stock 1268761 I by LLC Common Stock 95328 I by trust Common Stock 95327 I by trust Common Stock 95328 I by trust Held by Cherington Holdings LLC, of which the reporting person is a partner. Held by Ashley S. Pettus 2012 Irrevocable Trust FBO Benjamin P. Cherington, of which the reporting person is trustee. Held by Ashley S. Pettus 2012 Irrevocable Trust FBO Cyrus B. Cherington, of which the reporting person is trustee. Held by Ashley S. Pettus 2012 Irrevocable Trust FBO Henry S. Cherington, of which the reporting person is trustee. /s/ Charles Cherington 2022-09-14