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    <submissionType>SCHEDULE 13D/A</submissionType>
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          <!-- Field: Pseudo-Tag; ID: Name; Data: Bellevue Capital Partners, LLC -->
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          <ccc>XXXXXXXX</ccc>
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    <coverPageHeader>
      <amendmentNo>21</amendmentNo>
      <securitiesClassTitle>Class A common stock, $0.01 par value per share</securitiesClassTitle>
      <dateOfEvent>04/16/2025</dateOfEvent>
      <previouslyFiledFlag>false</previouslyFiledFlag>
      <issuerInfo>
        <issuerCIK>0001595527</issuerCIK>
        <issuerCUSIP>649439304</issuerCUSIP>
        <issuerName>American Strategic Investment Co.</issuerName>
        <address>
          <com:street1>222 Bellevue Avenue</com:street1>
          <com:city>Newport</com:city>
          <com:stateOrCountry>RI</com:stateOrCountry>
          <com:zipCode>02840</com:zipCode>
        </address>
      </issuerInfo>
      <authorizedPersons>
        <notificationInfo>
          <personName>Michael R. Anderson</personName>
          <personPhoneNum>212-415-6500</personPhoneNum>
          <personAddress>
            <com:street1>Bellevue Capital Partners, LLC</com:street1>
            <com:street2>222 Bellevue Avenue</com:street2>
            <com:city>Newport</com:city>
            <com:stateOrCountry>RI</com:stateOrCountry>
            <com:zipCode>02840</com:zipCode>
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        <fundType>WC</fundType>
        <legalProceedings>N</legalProceedings>
        <citizenshipOrOrganization>DE</citizenshipOrOrganization>
        <soleVotingPower>0.00</soleVotingPower>
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        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>1514958.00</sharedDispositivePower>
        <aggregateAmountOwned>1514958.00</aggregateAmountOwned>
        <isAggregateExcludeShares>N</isAggregateExcludeShares>
        <percentOfClass>57.5</percentOfClass>
        <typeOfReportingPerson>OO</typeOfReportingPerson>
      </reportingPersonInfo>
      <reportingPersonInfo>
        <reportingPersonNoCIK>Y</reportingPersonNoCIK>
        <reportingPersonName>AR Global Investments, LLC</reportingPersonName>
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        <legalProceedings>N</legalProceedings>
        <citizenshipOrOrganization>DE</citizenshipOrOrganization>
        <soleVotingPower>0.00</soleVotingPower>
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        <sharedDispositivePower>520666.00</sharedDispositivePower>
        <aggregateAmountOwned>520666.00</aggregateAmountOwned>
        <isAggregateExcludeShares>N</isAggregateExcludeShares>
        <percentOfClass>19.8</percentOfClass>
        <typeOfReportingPerson>OO</typeOfReportingPerson>
      </reportingPersonInfo>
      <reportingPersonInfo>
        <reportingPersonNoCIK>Y</reportingPersonNoCIK>
        <reportingPersonName>American Realty Capital III, LLC</reportingPersonName>
        <memberOfGroup>b</memberOfGroup>
        <fundType>OO</fundType>
        <legalProceedings>N</legalProceedings>
        <citizenshipOrOrganization>DE</citizenshipOrOrganization>
        <soleVotingPower>0.00</soleVotingPower>
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        <percentOfClass>19.8</percentOfClass>
        <typeOfReportingPerson>OO</typeOfReportingPerson>
      </reportingPersonInfo>
      <reportingPersonInfo>
        <reportingPersonNoCIK>Y</reportingPersonNoCIK>
        <reportingPersonName>New York City Special Limited Partnership, LLC</reportingPersonName>
        <memberOfGroup>b</memberOfGroup>
        <fundType>OO</fundType>
        <legalProceedings>N</legalProceedings>
        <citizenshipOrOrganization>DE</citizenshipOrOrganization>
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        <percentOfClass>19.8</percentOfClass>
        <typeOfReportingPerson>OO</typeOfReportingPerson>
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      <reportingPersonInfo>
        <reportingPersonNoCIK>Y</reportingPersonNoCIK>
        <reportingPersonName>New York City Advisors, LLC</reportingPersonName>
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        <legalProceedings>N</legalProceedings>
        <citizenshipOrOrganization>DE</citizenshipOrOrganization>
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        <typeOfReportingPerson>OO</typeOfReportingPerson>
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      <reportingPersonInfo>
        <reportingPersonNoCIK>Y</reportingPersonNoCIK>
        <reportingPersonName>Nicholas S. Schorsch</reportingPersonName>
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        <percentOfClass>58.5</percentOfClass>
        <typeOfReportingPerson>IN</typeOfReportingPerson>
      </reportingPersonInfo>
      <reportingPersonInfo>
        <reportingPersonNoCIK>Y</reportingPersonNoCIK>
        <reportingPersonName>Edward M. Weil, Jr.</reportingPersonName>
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        <fundType>OO</fundType>
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        <percentOfClass>0.0</percentOfClass>
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    </reportingPersons>
    <items1To7>
      <item1>
        <securityTitle>Class A common stock, $0.01 par value per share</securityTitle>
        <issuerName>American Strategic Investment Co.</issuerName>
        <issuerPrincipalAddress>
          <com:street1>222 Bellevue Avenue</com:street1>
          <com:city>Newport</com:city>
          <com:stateOrCountry>RI</com:stateOrCountry>
          <com:zipCode>02840</com:zipCode>
        </issuerPrincipalAddress>
        <commentText>This Amendment No. 21 (the "Amendment") to Schedule 13D amends and supplements the Schedule 13D originally filed with the United States Securities and Exchange Commission (the "SEC") on February 11, 2022 relating to the shares of Class A common stock, par value $0.01 per share (the "Class A Common Stock"), of American Strategic Investment Co. (f/k/a New York City REIT, Inc.), a Maryland corporation (the "Issuer"), as subsequently amended (the "Schedule 13D"). This Amendment updates the Schedule 13D to reflect certain recent transactions as reported under Item 3 below. Unless indicated otherwise, all items left blank remain unchanged and any items which are reported are deemed to amend and supplement the existing items in the Schedule 13D. Capitalized terms used herein without definition shall have the meaning set forth in the Original Schedule 13D.</commentText>
      </item1>
      <item3>
        <fundsSource>Item 3 of the Schedule 13D is amended and supplemented by inserting the following information: Bellevue Capital Partners. The transactions listed on Annex A attached hereto were open market purchased effected by Bellevue Capital Partners, LLC ("Bellevue Capital") from February 14, 2025 to April 15, 2025, inclusive and are incorporated by reference herein.</fundsSource>
      </item3>
      <item4>
        <transactionPurpose>Item 4 of the Schedule 13D is amended and supplemented by incorporating by reference the information set forth in Item 3 above.</transactionPurpose>
      </item4>
      <item5>
        <percentageOfClassSecurities>Item 5 of the Schedule 13D is amended and supplemented by incorporating by reference the information set forth in boxes (11) and (13) of the cover pages to this Amendment for each of the Reporting Persons, and such information is incorporated herein by reference. The percentages reported herein are calculated based upon 2,634,355 outstanding shares of Class A Common Stock as of March 14, 2025.</percentageOfClassSecurities>
        <numberOfShares>See Item 5(a).</numberOfShares>
        <transactionDesc>See Item 5(a).</transactionDesc>
        <listOfShareholders>See Item 5(a).</listOfShareholders>
        <date5PercentOwnership>See Item 5(a).</date5PercentOwnership>
      </item5>
      <item7>
        <filedExhibits>Annex A - Open Market Purchases</filedExhibits>
      </item7>
    </items1To7>
    <signatureInfo>
      <signaturePerson>
        <signatureReportingPerson>Bellevue Capital Partners, LLC</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Michael R. Anderson</signature>
          <title>General Counsel</title>
          <date>04/16/2025</date>
        </signatureDetails>
      </signaturePerson>
      <signaturePerson>
        <signatureReportingPerson>AR Global Investments, LLC</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Michael R. Anderson</signature>
          <title>General Counsel</title>
          <date>04/16/2025</date>
        </signatureDetails>
      </signaturePerson>
      <signaturePerson>
        <signatureReportingPerson>American Realty Capital III, LLC</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Michael R. Anderson</signature>
          <title>General Counsel</title>
          <date>04/16/2025</date>
        </signatureDetails>
      </signaturePerson>
      <signaturePerson>
        <signatureReportingPerson>New York City Special Limited Partnership, LLC</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Michael R. Anderson</signature>
          <title>General Counsel</title>
          <date>04/16/2025</date>
        </signatureDetails>
      </signaturePerson>
      <signaturePerson>
        <signatureReportingPerson>New York City Advisors, LLC</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Michael R. Anderson</signature>
          <title>Chief Executive Officer</title>
          <date>04/16/2025</date>
        </signatureDetails>
      </signaturePerson>
      <signaturePerson>
        <signatureReportingPerson>Nicholas S. Schorsch</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Michael R. Anderson</signature>
          <title>Attorney-in-Fact</title>
          <date>04/16/2025</date>
        </signatureDetails>
      </signaturePerson>
      <signaturePerson>
        <signatureReportingPerson>Edward M. Weil, Jr.</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Michael R. Anderson</signature>
          <title>Attorney-in-Fact</title>
          <date>04/16/2025</date>
        </signatureDetails>
      </signaturePerson>
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