The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
MICROSOFT CORP Common Stock 594918104   26,263 69,841 SH   SOLE   69,841 0 0
AMAZON.COM INC Common Stock 023135106   21,059 138,600 SH   SOLE   138,600 0 0
VERTEX PHARMACEUTICALS INC Common Stock 92532F100   15,497 38,087 SH   SOLE   38,087 0 0
ADOBE INC Common Stock 00724F101   12,859 21,554 SH   SOLE   21,554 0 0
NVIDIA CORP Common Stock 67066G104   12,457 25,155 SH   SOLE   25,155 0 0
META PLATFORMS INC-CLASS A Common Stock 30303M102   11,699 33,053 SH   SOLE   33,053 0 0
SERVICENOW INC Common Stock 81762P102   11,127 15,750 SH   SOLE   15,750 0 0
AMGEN INC Common Stock 031162100   9,183 31,884 SH   SOLE   31,884 0 0
REGENERON PHARMACEUTICALS Common Stock 75886F107   9,045 10,298 SH   SOLE   10,298 0 0
GILEAD SCIENCES INC Common Stock 375558103   8,989 110,962 SH   SOLE   110,962 0 0
TESLA INC Common Stock 88160R101   8,962 36,068 SH   SOLE   36,068 0 0
VISA INC-CLASS A SHARES Common Stock 92826C839   8,917 34,250 SH   SOLE   34,250 0 0
WORKDAY INC-CLASS A Common Stock 98138H101   8,508 30,819 SH   SOLE   30,819 0 0
ALPHABET INC-CL A Common Stock 02079K305   8,291 59,350 SH   SOLE   59,350 0 0
SALESFORCE INC Common Stock 79466L302   8,263 31,400 SH   SOLE   31,400 0 0
UBER TECHNOLOGIES INC Common Stock 90353T100   7,943 129,000 SH   SOLE   129,000 0 0
PALO ALTO NETWORKS INC Common Stock 697435105   7,880 26,723 SH   SOLE   26,723 0 0
BROADCOM INC Common Stock 11135F101   7,730 6,925 SH   SOLE   6,925 0 0
PDD HOLDINGS INC ADR 722304102   7,348 50,223 SH   SOLE   50,223 0 0
APPLE INC Common Stock 037833100   6,391 33,197 SH   SOLE   33,197 0 0
CROWDSTRIKE HOLDINGS INC - A Common Stock 22788C105   6,294 24,650 SH   SOLE   24,650 0 0
SYNOPSYS INC Common Stock 871607107   5,742 11,152 SH   SOLE   11,152 0 0
MERCK & CO. INC. Common Stock 58933Y105   5,507 50,193 SH   SOLE   50,193 0 0
BOOKING HOLDINGS INC Common Stock 09857L108   5,232 1,475 SH   SOLE   1,475 0 0
ADVANCED MICRO DEVICES Common Stock 007903107   5,052 34,270 SH   SOLE   34,270 0 0
ALNYLAM PHARMACEUTICALS INC Common Stock 02043Q107   5,007 26,160 SH   SOLE   26,160 0 0
BIOGEN INC Common Stock 09062X103   4,924 19,027 SH   SOLE   19,027 0 0
ELI LILLY & CO Common Stock 532457108   4,825 8,277 SH   SOLE   8,277 0 0
UNITEDHEALTH GROUP INC Common Stock 91324P102   4,743 9,010 SH   SOLE   9,010 0 0
MODERNA INC Common Stock 60770K107   4,540 45,655 SH   SOLE   45,655 0 0
TAIWAN SEMICONDUCTOR-SP ADR ADR 874039100   4,472 42,855 SH   SOLE   42,855 0 0
PROCTER & GAMBLE CO/THE Common Stock 742718109   4,447 30,344 SH   SOLE   30,344 0 0
QUALCOMM INC Common Stock 747525103   4,442 30,715 SH   SOLE   30,715 0 0
ASTRAZENECA PLC-SPONS ADR ADR 046353108   4,410 65,475 SH   SOLE   65,475 0 0
KLA CORP Common Stock 482480100   4,399 7,568 SH   SOLE   7,568 0 0
MICRON TECHNOLOGY INC Common Stock 595112103   4,372 51,167 SH   SOLE   51,167 0 0
MASTERCARD INC - A Common Stock 57636Q104   4,308 10,100 SH   SOLE   10,100 0 0
COSTCO WHOLESALE CORP Common Stock 22160K105   4,251 6,311 SH   SOLE   6,311 0 0
NOVO-NORDISK A/S-SPONS ADR ADR 670100205   4,231 40,896 SH   SOLE   40,896 0 0
NIKE INC -CL B Common Stock 654106103   4,184 38,489 SH   SOLE   38,489 0 0
VANGUARD EXTENDED DUR TREAS ETP 921910709   3,859 47,622 SH   SOLE   47,622 0 0
HOME DEPOT INC Common Stock 437076102   3,742 10,798 SH   SOLE   10,798 0 0
INTEL CORP Common Stock 458140100   3,735 74,320 SH   SOLE   74,320 0 0
CHIPOTLE MEXICAN GRILL INC Common Stock 169656105   3,680 1,609 SH   SOLE   1,609 0 0
DOORDASH INC - A Common Stock 25809K105   3,558 35,977 SH   SOLE   35,977 0 0
ON HOLDING AG-CLASS A Common Stock H5919C104   3,549 131,585 SH   SOLE   131,585 0 0
SHOPIFY INC - CLASS A Common Stock 82509L107   3,467 44,505 SH   SOLE   44,505 0 0
ATLASSIAN CORP-CL A Common Stock 049468101   3,355 14,106 SH   SOLE   14,106 0 0
WALMART INC Common Stock 931142103   3,159 20,005 SH   SOLE   20,005 0 0
DATADOG INC - CLASS A Common Stock 23804L103   3,107 25,598 SH   SOLE   25,598 0 0
DOLLAR GENERAL CORP Common Stock 256677105   3,004 22,097 SH   SOLE   22,097 0 0
SPDR GOLD MINISHARES TRUST ETP 98149E303   2,933 71,700 SH   SOLE   71,700 0 0
ALIBABA GROUP HOLDING-SP ADR ADR 01609W102   2,823 36,000 SH   SOLE   36,000 0 0
GOLDMAN SACHS PHYSICAL GOLD ETP 38150K103   2,820 138,000 SH   SOLE   138,000 0 0
LOWE'S COS INC Common Stock 548661107   2,695 12,108 SH   SOLE   12,108 0 0
ABRDN PHYSICAL GOLD SHARES ETP 00326A104   2,665 135,000 SH   SOLE   135,000 0 0
VAXCYTE INC Common Stock 92243G108   2,648 42,167 SH   SOLE   42,167 0 0
ILLUMINA INC Common Stock 452327109   2,622 18,829 SH   SOLE   18,829 0 0
SPDR GOLD SHARES ETP 78463V107   2,543 13,300 SH   SOLE   13,300 0 0
ISHARES GOLD TRUST ETP 464285204   2,537 65,000 SH   SOLE   65,000 0 0
COCA-COLA CO/THE Common Stock 191216100   2,499 42,412 SH   SOLE   42,412 0 0
BLOCK INC Common Stock 852234103   2,398 31,000 SH   SOLE   31,000 0 0
FORTINET INC Common Stock 34959E109   2,343 40,028 SH   SOLE   40,028 0 0
QUANTERIX CORP Common Stock 74766Q101   2,324 85,019 SH   SOLE   85,019 0 0
BIOMARIN PHARMACEUTICAL INC Common Stock 09061G101   2,136 22,156 SH   SOLE   22,156 0 0
TENCENT MUSIC ENTERTAINM-ADR ADR 88034P109   2,076 230,400 SH   SOLE   230,400 0 0
GSK PLC-SPON ADR ADR 37733W204   2,032 54,345 SH   SOLE   54,345 0 0
IDEXX LABORATORIES INC Common Stock 45168D104   2,016 3,632 SH   SOLE   3,632 0 0
HALOZYME THERAPEUTICS INC Common Stock 40637H109   1,999 54,081 SH   SOLE   54,081 0 0
INTUITIVE SURGICAL INC Common Stock 46120E602   1,860 5,513 SH   SOLE   5,513 0 0
ACADEMY SPORTS & OUTDOORS IN Common Stock 00402L107   1,842 27,904 SH   SOLE   27,904 0 0
MONOLITHIC POWER SYSTEMS INC Common Stock 609839105   1,832 2,900 SH   SOLE   2,900 0 0
POLARIS INC Common Stock 731068102   1,788 18,869 SH   SOLE   18,869 0 0
MARVELL TECHNOLOGY INC Common Stock 573874104   1,702 28,216 SH   SOLE   28,216 0 0
PEPSICO INC Common Stock 713448108   1,700 9,945 SH   SOLE   9,945 0 0
ULTA BEAUTY INC Common Stock 90384S303   1,660 3,387 SH   SOLE   3,387 0 0
RAMBUS INC Common Stock 750917106   1,638 24,000 SH   SOLE   24,000 0 0
INCYTE CORP Common Stock 45337C102   1,627 25,918 SH   SOLE   25,918 0 0
SANOFI-ADR ADR 80105N105   1,614 32,456 SH   SOLE   32,456 0 0
WOLFSPEED INC Common Stock 977852102   1,582 36,353 SH   SOLE   36,353 0 0
VIATRIS INC Common Stock 92556V106   1,503 138,771 SH   SOLE   138,771 0 0
NEUROCRINE BIOSCIENCES INC Common Stock 64125C109   1,497 11,364 SH   SOLE   11,364 0 0
ROYALTY PHARMA PLC- CL A Common Stock G7709Q104   1,451 51,672 SH   SOLE   51,672 0 0
NETFLIX INC Common Stock 64110L106   1,443 2,964 SH   SOLE   2,964 0 0
LI AUTO INC - ADR ADR 50202M102   1,422 38,000 SH   SOLE   38,000 0 0
FERRARI NV Common Stock N3167Y103   1,415 4,182 SH   SOLE   4,182 0 0
ARGENX SE - ADR ADR 04016X101   1,415 3,719 SH   SOLE   3,719 0 0
KARUNA THERAPEUTICS INC Common Stock 48576A100   1,381 4,363 SH   SOLE   4,363 0 0
TARGET CORP Common Stock 87612E106   1,315 9,236 SH   SOLE   9,236 0 0
ZILLOW GROUP INC - A Common Stock 98954M101   1,305 23,000 SH   SOLE   23,000 0 0
TRIP.COM GROUP LTD-ADR ADR 89677Q107   1,296 36,000 SH   SOLE   36,000 0 0
MCDONALD'S CORP Common Stock 580135101   1,229 4,144 SH   SOLE   4,144 0 0
KE HOLDINGS INC-ADR ADR 482497104   1,216 75,000 SH   SOLE   75,000 0 0
NETEASE INC-ADR ADR 64110W102   1,211 13,000 SH   SOLE   13,000 0 0
UNITED THERAPEUTICS CORP Common Stock 91307C102   1,196 5,437 SH   SOLE   5,437 0 0
BIONTECH SE-ADR ADR 09075V102   1,183 11,212 SH   SOLE   11,212 0 0
IQIYI INC-ADR ADR 46267X108   1,173 240,280 SH   SOLE   240,280 0 0
PAYPAL HOLDINGS INC Common Stock 70450Y103   1,167 19,001 SH   SOLE   19,001 0 0
STARBUCKS CORP Common Stock 855244109   1,140 11,875 SH   SOLE   11,875 0 0
SUPER MICRO COMPUTER INC Common Stock 86800U104   1,137 4,000 SH   SOLE   4,000 0 0
XPENG INC - ADR ADR 98422D105   1,129 77,400 SH   SOLE   77,400 0 0
DECKERS OUTDOOR CORP Common Stock 243537107   1,119 1,674 SH   SOLE   1,674 0 0
MEDPACE HOLDINGS INC Common Stock 58506Q109   1,090 3,555 SH   SOLE   3,555 0 0
WALT DISNEY CO/THE Common Stock 254687106   1,086 11,991 SH   SOLE   11,991 0 0
ROIVANT SCIENCES LTD Common Stock G76279101   1,044 92,989 SH   SOLE   92,989 0 0
SAREPTA THERAPEUTICS INC Common Stock 803607100   1,044 10,824 SH   SOLE   10,824 0 0
DIAGEO PLC-SPONSORED ADR ADR 25243Q205   1,010 6,934 SH   SOLE   6,934 0 0
GILDAN ACTIVEWEAR INC Common Stock 375916103   968 29,279 SH   SOLE   29,279 0 0
CYTOKINETICS INC Common Stock 23282W605   947 11,341 SH   SOLE   11,341 0 0
PINTEREST INC- CLASS A Common Stock 72352L106   926 25,000 SH   SOLE   25,000 0 0
IMMUNOGEN INC Common Stock 45253H101   918 30,961 SH   SOLE   30,961 0 0
ALLEGRO MICROSYSTEMS INC Common Stock 01749D105   908 30,000 SH   SOLE   30,000 0 0
JAZZ PHARMACEUTICALS PLC Common Stock G50871105   895 7,280 SH   SOLE   7,280 0 0
DOLLAR TREE INC Common Stock 256746108   880 6,194 SH   SOLE   6,194 0 0
BEIGENE LTD-ADR ADR 07725L102   876 4,856 SH   SOLE   4,856 0 0
EXELIXIS INC Common Stock 30161Q104   863 35,975 SH   SOLE   35,975 0 0
ASML HOLDING NV-NY REG SHS NY Reg Shrs N07059210   850 1,123 SH   SOLE   1,123 0 0
ROYAL CARIBBEAN CRUISES LTD Common Stock V7780T103   847 6,538 SH   SOLE   6,538 0 0
IONIS PHARMACEUTICALS INC Common Stock 462222100   840 16,598 SH   SOLE   16,598 0 0
ASCENDIS PHARMA A/S - ADR ADR 04351P101   836 6,635 SH   SOLE   6,635 0 0
BATH & BODY WORKS INC Common Stock 070830104   833 19,305 SH   SOLE   19,305 0 0
APELLIS PHARMACEUTICALS INC Common Stock 03753U106   821 13,710 SH   SOLE   13,710 0 0
BRIDGEBIO PHARMA INC Common Stock 10806X102   812 20,120 SH   SOLE   20,120 0 0
INTRA-CELLULAR THERAPIES INC Common Stock 46116X101   797 11,133 SH   SOLE   11,133 0 0
SPDR S&P BIOTECH ETF ETP 78464A870   795 8,904 SH   SOLE   8,904 0 0
DOMINO'S PIZZA INC Common Stock 25754A201   778 1,888 SH   SOLE   1,888 0 0
CROCS INC Common Stock 227046109   726 7,775 SH   SOLE   7,775 0 0
IMMUNOVANT INC Common Stock 45258J102   705 16,734 SH   SOLE   16,734 0 0
ISHARES SILVER TRUST ETP 46428Q109   653 30,000 SH   SOLE   30,000 0 0
BLUEPRINT MEDICINES CORP Common Stock 09627Y109   649 7,032 SH   SOLE   7,032 0 0
SKECHERS USA INC-CL A Common Stock 830566105   647 10,374 SH   SOLE   10,374 0 0
ISHARES GOLD TRUST MICRO ETP 46436F103   639 31,000 SH   SOLE   31,000 0 0
ALPHABET INC-CL C Common Stock 02079K107   620 4,401 SH   SOLE   4,401 0 0
TYSON FOODS INC-CL A Common Stock 902494103   610 11,344 SH   SOLE   11,344 0 0
ACADIA PHARMACEUTICALS INC Common Stock 004225108   594 18,985 SH   SOLE   18,985 0 0
CRISPR THERAPEUTICS AG Common Stock H17182108   575 9,193 SH   SOLE   9,193 0 0
ON SEMICONDUCTOR Common Stock 682189105   573 6,856 SH   SOLE   6,856 0 0
HILTON WORLDWIDE HOLDINGS IN Common Stock 43300A203   568 3,122 SH   SOLE   3,122 0 0
LEGEND BIOTECH CORP-ADR ADR 52490G102   555 9,222 SH   SOLE   9,222 0 0
CARNIVAL CORP Common Stock 143658300   547 29,500 SH   SOLE   29,500 0 0
REVOLUTION MEDICINES INC Common Stock 76155X100   543 18,941 SH   SOLE   18,941 0 0
ALKERMES PLC Common Stock G01767105   536 19,306 SH   SOLE   19,306 0 0
MADRIGAL PHARMACEUTICALS INC Common Stock 558868105   530 2,292 SH   SOLE   2,292 0 0
ATOUR LIFESTYLE HOLDINGS-ADR ADR 04965M106   515 29,667 SH   SOLE   29,667 0 0
INSMED INC Common Stock 457669307   513 16,551 SH   SOLE   16,551 0 0
PROSHARES ULTRA GOLD ETP 74347W601   511 8,000 SH   SOLE   8,000 0 0
EXPEDIA GROUP INC Common Stock 30212P303   505 3,330 SH   SOLE   3,330 0 0
NUVALENT INC-A Common Stock 670703107   487 6,619 SH   SOLE   6,619 0 0
AMICUS THERAPEUTICS INC Common Stock 03152W109   481 33,920 SH   SOLE   33,920 0 0
MIRATI THERAPEUTICS INC Common Stock 60468T105   477 8,117 SH   SOLE   8,117 0 0
ULTRAGENYX PHARMACEUTICAL IN Common Stock 90400D108   454 9,501 SH   SOLE   9,501 0 0
AXSOME THERAPEUTICS INC Common Stock 05464T104   436 5,475 SH   SOLE   5,475 0 0
ROBLOX CORP -CLASS A Common Stock 771049103   424 9,284 SH   SOLE   9,284 0 0
CISCO SYSTEMS INC Common Stock 17275R102   408 8,084 SH   SOLE   8,084 0 0
GRANITESHARES GOLD TRUST ETP 38748G101   408 20,000 SH   SOLE   20,000 0 0
KRYSTAL BIOTECH INC Common Stock 501147102   404 3,259 SH   SOLE   3,259 0 0
ANALOG DEVICES INC Common Stock 032654105   395 1,991 SH   SOLE   1,991 0 0
XENON PHARMACEUTICALS INC Common Stock 98420N105   394 8,546 SH   SOLE   8,546 0 0
IMMUNITYBIO INC Common Stock 45256X103   388 77,235 SH   SOLE   77,235 0 0
ARROWHEAD PHARMACEUTICALS IN Common Stock 04280A100   380 12,429 SH   SOLE   12,429 0 0
T-MOBILE US INC Common Stock 872590104   371 2,314 SH   SOLE   2,314 0 0
GUARDANT HEALTH INC Common Stock 40131M109   369 13,652 SH   SOLE   13,652 0 0
FORTREA HOLDINGS INC Common Stock 34965K107   358 10,268 SH   SOLE   10,268 0 0
COMCAST CORP-CLASS A Common Stock 20030N101   351 8,007 SH   SOLE   8,007 0 0
INTUIT INC Common Stock 461202103   348 556 SH   SOLE   556 0 0
AMPHASTAR PHARMACEUTICALS IN Common Stock 03209R103   343 5,542 SH   SOLE   5,542 0 0
DENALI THERAPEUTICS INC Common Stock 24823R105   343 15,981 SH   SOLE   15,981 0 0
AUTOLIV INC Common Stock 052800109   331 3,000 SH   SOLE   3,000 0 0
PACIFIC BIOSCIENCES OF CALIF Common Stock 69404D108   322 32,855 SH   SOLE   32,855 0 0
INTELLIA THERAPEUTICS INC Common Stock 45826J105   316 10,355 SH   SOLE   10,355 0 0
RHYTHM PHARMACEUTICALS INC Common Stock 76243J105   314 6,837 SH   SOLE   6,837 0 0
ARCELLX INC Common Stock 03940C100   313 5,632 SH   SOLE   5,632 0 0
ROCKET PHARMACEUTICALS INC Common Stock 77313F106   312 10,424 SH   SOLE   10,424 0 0
CYMABAY THERAPEUTICS INC Common Stock 23257D103   310 13,114 SH   SOLE   13,114 0 0
TEXAS INSTRUMENTS INC Common Stock 882508104   309 1,811 SH   SOLE   1,811 0 0
YUM! BRANDS INC Common Stock 988498101   299 2,285 SH   SOLE   2,285 0 0
VERONA PHARMA PLC - ADR ADR 925050106   296 14,878 SH   SOLE   14,878 0 0
CATALENT INC Common Stock 148806102   283 6,301 SH   SOLE   6,301 0 0
HONEYWELL INTERNATIONAL INC Common Stock 438516106   275 1,312 SH   SOLE   1,312 0 0
CRINETICS PHARMACEUTICALS IN Common Stock 22663K107   275 7,721 SH   SOLE   7,721 0 0
APPLIED MATERIALS INC Common Stock 038222105   268 1,652 SH   SOLE   1,652 0 0
IMMUNOCORE HOLDINGS PLC-ADR ADR 45258D105   266 3,900 SH   SOLE   3,900 0 0
IDEAYA BIOSCIENCES INC Common Stock 45166A102   265 7,453 SH   SOLE   7,453 0 0
SPRINGWORKS THERAPEUTICS INC Common Stock 85205L107   264 7,237 SH   SOLE   7,237 0 0
BEAM THERAPEUTICS INC Common Stock 07373V105   263 9,667 SH   SOLE   9,667 0 0
ARVINAS INC Common Stock 04335A105   262 6,370 SH   SOLE   6,370 0 0
FULL TRUCK ALLIANCE -SPN ADR ADR 35969L108   260 37,130 SH   SOLE   37,130 0 0
TWIST BIOSCIENCE CORP Common Stock 90184D100   246 6,674 SH   SOLE   6,674 0 0
IOVANCE BIOTHERAPEUTICS INC Common Stock 462260100   241 29,602 SH   SOLE   29,602 0 0
PTC THERAPEUTICS INC Common Stock 69366J200   241 8,727 SH   SOLE   8,727 0 0
RECURSION PHARMACEUTICALS-A Common Stock 75629V104   238 24,091 SH   SOLE   24,091 0 0
VF CORP Common Stock 918204108   234 12,460 SH   SOLE   12,460 0 0
VERACYTE INC Common Stock 92337F107   232 8,448 SH   SOLE   8,448 0 0
SCHRODINGER INC Common Stock 80810D103   229 6,410 SH   SOLE   6,410 0 0
PROTHENA CORP PLC Common Stock G72800108   225 6,203 SH   SOLE   6,203 0 0
CHARGEPOINT HOLDINGS INC Common Stock 15961R105   222 95,000 SH   SOLE   95,000 0 0
HARMONY BIOSCIENCES HOLDINGS Common Stock 413197104   219 6,777 SH   SOLE   6,777 0 0
LEVI STRAUSS & CO- CLASS A Common Stock 52736R102   215 12,970 SH   SOLE   12,970 0 0
SUMMIT THERAPEUTICS INC Common Stock 86627T108   212 81,071 SH   SOLE   81,071 0 0
DYNAVAX TECHNOLOGIES CORP Common Stock 268158201   209 14,956 SH   SOLE   14,956 0 0
INHIBRX INC Common Stock 45720L107   208 5,471 SH   SOLE   5,471 0 0
IRONWOOD PHARMACEUTICALS INC Common Stock 46333X108   207 18,061 SH   SOLE   18,061 0 0
LAM RESEARCH CORP Common Stock 512807108   204 260 SH   SOLE   260 0 0
DANAHER CORP Common Stock 235851102   202 871 SH   SOLE   871 0 0
MONDELEZ INTERNATIONAL INC-A Common Stock 609207105   197 2,707 SH   SOLE   2,707 0 0
VERICEL CORP Common Stock 92346J108   197 5,521 SH   SOLE   5,521 0 0
MYRIAD GENETICS INC Common Stock 62855J104   196 10,253 SH   SOLE   10,253 0 0
ZOETIS INC Common Stock 98978V103   195 986 SH   SOLE   986 0 0
AUTOMATIC DATA PROCESSING Common Stock 053015103   192 821 SH   SOLE   821 0 0
ABCELLERA BIOLOGICS INC Common Stock 00288U106   192 33,566 SH   SOLE   33,566 0 0
NOVOCURE LTD Common Stock G6674U108   185 12,363 SH   SOLE   12,363 0 0
MERUS NV Common Stock N5749R100   184 6,681 SH   SOLE   6,681 0 0
SUPERNUS PHARMACEUTICALS INC Common Stock 868459108   183 6,314 SH   SOLE   6,314 0 0
PACIRA BIOSCIENCES INC Common Stock 695127100   181 5,373 SH   SOLE   5,373 0 0
HESAI GROUP ADR 428050108   178 20,000 SH   SOLE   20,000 0 0
STRUCTURE THERAPEUTICS INC ADR 86366E106   177 4,349 SH   SOLE   4,349 0 0
ZOOM VIDEO COMMUNICATIONS-A Common Stock 98980L101   175 2,440 SH   SOLE   2,440 0 0
SYNDAX PHARMACEUTICALS INC Common Stock 87164F105   174 8,058 SH   SOLE   8,058 0 0
CONSTELLATION BRANDS INC-A Common Stock 21036P108   172 713 SH   SOLE   713 0 0
ARDELYX INC Common Stock 039697107   166 26,851 SH   SOLE   26,851 0 0
MORPHIC HOLDING INC Common Stock 61775R105   166 5,753 SH   SOLE   5,753 0 0
KYMERA THERAPEUTICS INC Common Stock 501575104   164 6,423 SH   SOLE   6,423 0 0
GRIFOLS SA-ADR ADR 398438408   163 14,111 SH   SOLE   14,111 0 0
LULULEMON ATHLETICA INC Common Stock 550021109   161 315 SH   SOLE   315 0 0
DISC MEDICINE INC Common Stock 254604101   161 2,793 SH   SOLE   2,793 0 0
MIRUM PHARMACEUTICALS INC Common Stock 604749101   159 5,394 SH   SOLE   5,394 0 0
ZAI LAB LTD-ADR ADR 98887Q104   159 5,802 SH   SOLE   5,802 0 0
MERCADOLIBRE INC Common Stock 58733R102   157 100 SH   SOLE   100 0 0
RELAY THERAPEUTICS INC Common Stock 75943R102   157 14,257 SH   SOLE   14,257 0 0
SCHOLAR ROCK HOLDING CORP Common Stock 80706P103   157 8,346 SH   SOLE   8,346 0 0
VIR BIOTECHNOLOGY INC Common Stock 92764N102   157 15,560 SH   SOLE   15,560 0 0
APOGEE THERAPEUTICS INC Common Stock 03770N101   155 5,555 SH   SOLE   5,555 0 0
GENMAB A/S -SP ADR ADR 372303206   154 4,845 SH   SOLE   4,845 0 0
PROTAGONIST THERAPEUTICS INC Common Stock 74366E102   153 6,675 SH   SOLE   6,675 0 0
AKERO THERAPEUTICS INC Common Stock 00973Y108   151 6,449 SH   SOLE   6,449 0 0
DECIPHERA PHARMACEUTICALS IN Common Stock 24344T101   150 9,272 SH   SOLE   9,272 0 0
SAGE THERAPEUTICS INC Common Stock 78667J108   150 6,937 SH   SOLE   6,937 0 0
AURINIA PHARMACEUTICALS INC Common Stock 05156V102   149 16,613 SH   SOLE   16,613 0 0
XENCOR INC Common Stock 98401F105   149 7,041 SH   SOLE   7,041 0 0
VEEVA SYSTEMS INC-CLASS A Common Stock 922475108   148 771 SH   SOLE   771 0 0
CADENCE DESIGN SYS INC Common Stock 127387108   147 538 SH   SOLE   538 0 0
DAY ONE BIOPHARMACEUTICALS I Common Stock 23954D109   147 10,067 SH   SOLE   10,067 0 0
AVADEL PHARMACEUTICALS-ADR ADR 05337M104   146 10,327 SH   SOLE   10,327 0 0
AGIOS PHARMACEUTICALS INC Common Stock 00847X104   144 6,469 SH   SOLE   6,469 0 0
LIGAND PHARMACEUTICALS Common Stock 53220K504   144 2,012 SH   SOLE   2,012 0 0
BIOCRYST PHARMACEUTICALS INC Common Stock 09058V103   142 23,692 SH   SOLE   23,692 0 0
KEROS THERAPEUTICS INC Common Stock 492327101   138 3,460 SH   SOLE   3,460 0 0
CSX CORP Common Stock 126408103   137 3,939 SH   SOLE   3,939 0 0
GERON CORP Common Stock 374163103   133 62,820 SH   SOLE   62,820 0 0
MARRIOTT INTERNATIONAL -CL A Common Stock 571903202   131 583 SH   SOLE   583 0 0
ANI PHARMACEUTICALS INC Common Stock 00182C103   131 2,367 SH   SOLE   2,367 0 0
ALPINE IMMUNE SCIENCES INC Common Stock 02083G100   128 6,723 SH   SOLE   6,723 0 0
PLIANT THERAPEUTICS INC Common Stock 729139105   125 6,929 SH   SOLE   6,929 0 0
KURA ONCOLOGY INC Common Stock 50127T109   124 8,590 SH   SOLE   8,590 0 0
ZENTALIS PHARMACEUTICALS INC Common Stock 98943L107   124 8,188 SH   SOLE   8,188 0 0
DEXCOM INC Common Stock 252131107   123 994 SH   SOLE   994 0 0
VERVE THERAPEUTICS INC Common Stock 92539P101   123 8,815 SH   SOLE   8,815 0 0
CINTAS CORP Common Stock 172908105   121 201 SH   SOLE   201 0 0
AIRBNB INC-CLASS A Common Stock 009066101   119 875 SH   SOLE   875 0 0
MONSTER BEVERAGE CORP Common Stock 61174X109   119 2,071 SH   SOLE   2,071 0 0
INNOVIVA INC Common Stock 45781M101   119 7,410 SH   SOLE   7,410 0 0
NXP SEMICONDUCTORS NV Common Stock N6596X109   118 510 SH   SOLE   510 0 0
ADMA BIOLOGICS INC Common Stock 000899104   118 26,142 SH   SOLE   26,142 0 0
TANGO THERAPEUTICS INC Common Stock 87583X109   117 11,793 SH   SOLE   11,793 0 0
ROPER TECHNOLOGIES INC Common Stock 776696106   116 213 SH   SOLE   213 0 0
COLLEGIUM PHARMACEUTICAL INC Common Stock 19459J104   116 3,776 SH   SOLE   3,776 0 0
CHARTER COMMUNICATIONS INC-A Common Stock 16119P108   115 295 SH   SOLE   295 0 0
AMYLYX PHARMACEUTICALS INC Common Stock 03237H101   115 7,815 SH   SOLE   7,815 0 0
CABALETTA BIO INC Common Stock 12674W109   113 4,962 SH   SOLE   4,962 0 0
MANNKIND CORP Common Stock 56400P706   113 31,180 SH   SOLE   31,180 0 0
O'REILLY AUTOMOTIVE INC Common Stock 67103H107   111 117 SH   SOLE   117 0 0
CUREVAC NV Common Stock N2451R105   109 25,887 SH   SOLE   25,887 0 0
AUTOLUS THERAPEUTICS PLC ADR 05280R100   105 16,263 SH   SOLE   16,263 0 0
PACCAR INC Common Stock 693718108   104 1,040 SH   SOLE   1,040 0 0
NEW AMBRX BIOPHARMA INC Common Stock 641871108   104 7,303 SH   SOLE   7,303 0 0
AUTODESK INC Common Stock 052769106   103 425 SH   SOLE   425 0 0
4D MOLECULAR THERAPEUTICS IN Common Stock 35104E100   100 4,951 SH   SOLE   4,951 0 0
MARAVAI LIFESCIENCES HLDGS-A Common Stock 56600D107   100 15,292 SH   SOLE   15,292 0 0
PRIME MEDICINE INC Common Stock 74168J101   100 11,258 SH   SOLE   11,258 0 0
AMPHENOL CORP-CL A Common Stock 032095101   99 1,000 SH   SOLE   1,000 0 0
RAPT THERAPEUTICS INC Common Stock 75382E109   99 3,981 SH   SOLE   3,981 0 0
89BIO INC Common Stock 282559103   98 8,747 SH   SOLE   8,747 0 0
MICROCHIP TECHNOLOGY INC Common Stock 595017104   97 1,072 SH   SOLE   1,072 0 0
ARCTURUS THERAPEUTICS HOLDIN Common Stock 03969T109   97 3,089 SH   SOLE   3,089 0 0
EDITAS MEDICINE INC Common Stock 28106W103   96 9,450 SH   SOLE   9,450 0 0
TJX COMPANIES INC Common Stock 872540109   94 1,000 SH   SOLE   1,000 0 0
COPART INC Common Stock 217204106   94 1,910 SH   SOLE   1,910 0 0
ROSS STORES INC Common Stock 778296103   94 677 SH   SOLE   677 0 0
DYNE THERAPEUTICS INC Common Stock 26818M108   94 7,099 SH   SOLE   7,099 0 0
EYEPOINT PHARMACEUTICALS INC Common Stock 30233G209   94 4,085 SH   SOLE   4,085 0 0
KEURIG DR PEPPER INC Common Stock 49271V100   93 2,800 SH   SOLE   2,800 0 0
SANA BIOTECHNOLOGY INC Common Stock 799566104   93 22,800 SH   SOLE   22,800 0 0
GALAPAGOS NV-SPON ADR ADR 36315X101   92 2,265 SH   SOLE   2,265 0 0
KRAFT HEINZ CO/THE Common Stock 500754106   91 2,453 SH   SOLE   2,453 0 0
ICOSAVAX INC Common Stock 45114M109   91 5,793 SH   SOLE   5,793 0 0
REGENXBIO INC Common Stock 75901B107   91 5,093 SH   SOLE   5,093 0 0
OLEMA PHARMACEUTICALS INC Common Stock 68062P106   89 6,341 SH   SOLE   6,341 0 0
REVANCE THERAPEUTICS INC Common Stock 761330109   89 10,155 SH   SOLE   10,155 0 0
OLD DOMINION FREIGHT LINE Common Stock 679580100   88 216 SH   SOLE   216 0 0
ANAVEX LIFE SCIENCES CORP Common Stock 032797300   88 9,498 SH   SOLE   9,498 0 0
PAYCHEX INC Common Stock 704326107   86 721 SH   SOLE   721 0 0
ALX ONCOLOGY HOLDINGS INC Common Stock 00166B105   86 5,762 SH   SOLE   5,762 0 0
AMERICAN ELECTRIC POWER Common Stock 025537101   85 1,052 SH   SOLE   1,052 0 0
GRACELL BIOTECHNOLOGIES-ADR ADR 38406L103   84 8,405 SH   SOLE   8,405 0 0
ACELYRIN INC Common Stock 00445A100   84 11,259 SH   SOLE   11,259 0 0
ZYMEWORKS INC Common Stock 98985Y108   84 8,100 SH   SOLE   8,100 0 0
OMNIAB INC Common Stock 68218J103   83 13,450 SH   SOLE   13,450 0 0
ADAPTIVE BIOTECHNOLOGIES Common Stock 00650F109   82 16,747 SH   SOLE   16,747 0 0
DINGDONG CAYMAN LTD -SPN ADR ADR 25445D101   80 53,514 SH   SOLE   53,514 0 0
EDGEWISE THERAPEUTICS INC Common Stock 28036F105   80 7,338 SH   SOLE   7,338 0 0
FUSION PHARMACEUTICALS INC Common Stock 36118A100   80 8,376 SH   SOLE   8,376 0 0
VERA THERAPEUTICS INC Common Stock 92337R101   79 5,143 SH   SOLE   5,143 0 0
ALECTOR INC Common Stock 014442107   78 9,733 SH   SOLE   9,733 0 0
AVIDITY BIOSCIENCES INC Common Stock 05370A108   78 8,570 SH   SOLE   8,570 0 0
TARSUS PHARMACEUTICALS INC Common Stock 87650L103   78 3,832 SH   SOLE   3,832 0 0
TRAVERE THERAPEUTICS INC Common Stock 89422G107   78 8,690 SH   SOLE   8,690 0 0
COGNIZANT TECH SOLUTIONS-A Common Stock 192446102   76 1,000 SH   SOLE   1,000 0 0
CONSTELLATION ENERGY Common Stock 21037T109   74 633 SH   SOLE   633 0 0
SAVARA INC Common Stock 805111101   74 15,654 SH   SOLE   15,654 0 0
ELECTRONIC ARTS INC Common Stock 285512109   73 535 SH   SOLE   535 0 0
FASTENAL CO Common Stock 311900104   73 1,127 SH   SOLE   1,127 0 0
EXELON CORP Common Stock 30161N101   72 2,003 SH   SOLE   2,003 0 0
BICYCLE THERAPEUTICS PLC-ADR ADR 088786108   72 4,001 SH   SOLE   4,001 0 0
KINIKSA PHARMACEUTICALS-A Common Stock G5269C101   72 4,097 SH   SOLE   4,097 0 0
COSTAR GROUP INC Common Stock 22160N109   71 816 SH   SOLE   816 0 0
GE HEALTHCARE TECHNOLOGY Common Stock 36266G107   70 903 SH   SOLE   903 0 0
EVOLUS INC Common Stock 30052C107   70 6,614 SH   SOLE   6,614 0 0
VERISK ANALYTICS INC Common Stock 92345Y106   69 289 SH   SOLE   289 0 0
XCEL ENERGY INC Common Stock 98389B100   69 1,103 SH   SOLE   1,103 0 0
MACROGENICS INC Common Stock 556099109   69 7,174 SH   SOLE   7,174 0 0
MARINUS PHARMACEUTICALS INC Common Stock 56854Q200   69 6,307 SH   SOLE   6,307 0 0
BAKER HUGHES CO Common Stock 05722G100   68 1,985 SH   SOLE   1,985 0 0
CASTLE BIOSCIENCES INC Common Stock 14843C105   67 3,110 SH   SOLE   3,110 0 0
PETIQ INC Common Stock 71639T106   67 3,372 SH   SOLE   3,372 0 0
ANAPTYSBIO INC Common Stock 032724106   66 3,072 SH   SOLE   3,072 0 0
ENLIVEN THERAPEUTICS INC Common Stock 29337E102   66 4,763 SH   SOLE   4,763 0 0
NOVAVAX INC Common Stock 670002401   66 13,743 SH   SOLE   13,743 0 0
GLOBALFOUNDRIES INC Common Stock G39387108   65 1,080 SH   SOLE   1,080 0 0
ZSCALER INC Common Stock 98980G102   65 294 SH   SOLE   294 0 0
HUTCHMED CHINA-ADR ADR 44842L103   65 3,593 SH   SOLE   3,593 0 0
THERAVANCE BIOPHARMA INC Common Stock G8807B106   65 5,759 SH   SOLE   5,759 0 0
ANSYS INC Common Stock 03662Q105   63 174 SH   SOLE   174 0 0
TRADE DESK INC/THE -CLASS A Common Stock 88339J105   63 880 SH   SOLE   880 0 0
ALLOGENE THERAPEUTICS INC Common Stock 019770106   62 19,467 SH   SOLE   19,467 0 0
TOURMALINE BIO INC Common Stock 89157D105   62 2,357 SH   SOLE   2,357 0 0
AMBARELLA INC Common Stock G037AX101   61 1,000 SH   SOLE   1,000 0 0
COCA-COLA EUROPACIFIC PARTNE Common Stock G25839104   61 909 SH   SOLE   909 0 0
ARS PHARMACEUTICALS INC Common Stock 82835W108   61 11,105 SH   SOLE   11,105 0 0
CDW CORP/DE Common Stock 12514G108   60 266 SH   SOLE   266 0 0
BIOMEA FUSION INC Common Stock 09077A106   60 4,131 SH   SOLE   4,131 0 0
PHATHOM PHARMACEUTICALS INC Common Stock 71722W107   60 6,626 SH   SOLE   6,626 0 0
COGENT BIOSCIENCES INC Common Stock 19240Q201   59 9,961 SH   SOLE   9,961 0 0
CARIBOU BIOSCIENCES INC Common Stock 142038108   59 10,226 SH   SOLE   10,226 0 0
MONGODB INC Common Stock 60937P106   58 141 SH   SOLE   141 0 0
NURIX THERAPEUTICS INC Common Stock 67080M103   58 5,611 SH   SOLE   5,611 0 0
ORIC PHARMACEUTICALS INC Common Stock 68622P109   58 6,305 SH   SOLE   6,305 0 0
REPLIMUNE GROUP INC Common Stock 76029N106   58 6,833 SH   SOLE   6,833 0 0
WAVE LIFE SCIENCES LTD Common Stock Y95308105   58 11,456 SH   SOLE   11,456 0 0
JANUX THERAPEUTICS INC Common Stock 47103J105   57 5,343 SH   SOLE   5,343 0 0
LYELL IMMUNOPHARMA INC Common Stock 55083R104   57 29,137 SH   SOLE   29,137 0 0
WARNER BROS DISCOVERY INC Common Stock 934423104   56 4,932 SH   SOLE   4,932 0 0
MAXCYTE INC Common Stock 57777K106   56 11,986 SH   SOLE   11,986 0 0
DIAMONDBACK ENERGY INC Common Stock 25278X109   55 353 SH   SOLE   353 0 0
TAKE-TWO INTERACTIVE SOFTWRE Common Stock 874054109   55 339 SH   SOLE   339 0 0
UROGEN PHARMA LTD Common Stock M96088105   54 3,575 SH   SOLE   3,575 0 0
MEIRAGTX HOLDINGS PLC Common Stock G59665102   52 7,354 SH   SOLE   7,354 0 0
SPLUNK INC Common Stock 848637104   51 335 SH   SOLE   335 0 0
CENTESSA PHARMACEUTICALS-ADR ADR 152309100   51 6,394 SH   SOLE   6,394 0 0
THIRD HARMONIC BIO INC Common Stock 88427A107   51 4,665 SH   SOLE   4,665 0 0
CULLINAN ONCOLOGY INC Common Stock 230031106   50 4,954 SH   SOLE   4,954 0 0
CANAAN INC ADR 134748102   49 21,000 SH   SOLE   21,000 0 0
ARBUTUS BIOPHARMA CORP Common Stock 03879J100   49 19,400 SH   SOLE   19,400 0 0
KALVISTA PHARMACEUTICALS INC Common Stock 483497103   49 3,981 SH   SOLE   3,981 0 0
AC IMMUNE SA Common Stock H00263105   48 9,674 SH   SOLE   9,674 0 0
FULCRUM THERAPEUTICS INC Common Stock 359616109   48 7,150 SH   SOLE   7,150 0 0
HARROW INC Common Stock 415858109   46 4,063 SH   SOLE   4,063 0 0
SIGA TECHNOLOGIES INC Common Stock 826917106   46 8,225 SH   SOLE   8,225 0 0
TERNS PHARMACEUTICALS INC Common Stock 880881107   46 7,147 SH   SOLE   7,147 0 0
WALGREENS BOOTS ALLIANCE INC Common Stock 931427108   45 1,715 SH   SOLE   1,715 0 0
ITEOS THERAPEUTICS INC Common Stock 46565G104   45 4,140 SH   SOLE   4,140 0 0
COHERUS BIOSCIENCES INC Common Stock 19249H103   43 12,880 SH   SOLE   12,880 0 0
LEXICON PHARMACEUTICALS INC Common Stock 528872302   43 28,329 SH   SOLE   28,329 0 0
NAUTILUS BIOTECHNOLOGY INC Common Stock 63909J108   43 14,452 SH   SOLE   14,452 0 0
VOYAGER THERAPEUTICS INC Common Stock 92915B106   43 5,093 SH   SOLE   5,093 0 0
UNIQURE NV Common Stock N90064101   42 6,258 SH   SOLE   6,258 0 0
SIRIUS XM HOLDINGS INC Common Stock 82968B103   42 7,701 SH   SOLE   7,701 0 0
MINERALYS THERAPEUTICS INC Common Stock 603170101   41 4,750 SH   SOLE   4,750 0 0
OCULAR THERAPEUTIX INC Common Stock 67576A100   41 9,192 SH   SOLE   9,192 0 0
UNITY SOFTWARE INC Common Stock 91332U101   39 961 SH   SOLE   961 0 0
AMARIN CORP PLC -ADR ADR 023111206   39 44,599 SH   SOLE   44,599 0 0
PRECIGEN INC Common Stock 74017N105   39 28,788 SH   SOLE   28,788 0 0
TAYSHA GENE THERAPIES INC Common Stock 877619106   38 21,622 SH   SOLE   21,622 0 0
XERIS BIOPHARMA HOLDINGS INC Common Stock 98422E103   38 15,973 SH   SOLE   15,973 0 0
ERASCA INC Common Stock 29479A108   37 17,472 SH   SOLE   17,472 0 0
ALIGN TECHNOLOGY INC Common Stock 016255101   36 133 SH   SOLE   133 0 0
ARCUTIS BIOTHERAPEUTICS INC Common Stock 03969K108   35 10,920 SH   SOLE   10,920 0 0
EXSCIENTIA PLC ADR 30223G102   34 5,245 SH   SOLE   5,245 0 0
HUMACYTE INC Common Stock 44486Q103   34 11,986 SH   SOLE   11,986 0 0
Y-MABS THERAPEUTICS INC Common Stock 984241109   34 5,050 SH   SOLE   5,050 0 0
23ANDME HOLDING CO -CLASS A Common Stock 90138Q108   33 36,049 SH   SOLE   36,049 0 0
HYATT HOTELS CORP - CL A Common Stock 448579102   31 240 SH   SOLE   240 0 0
ATEA PHARMACEUTICALS INC Common Stock 04683R106   29 9,653 SH   SOLE   9,653 0 0
VANDA PHARMACEUTICALS INC Common Stock 921659108   28 6,658 SH   SOLE   6,658 0 0
ATAI LIFE SCIENCES NV Common Stock N0731H103   27 19,206 SH   SOLE   19,206 0 0
PHIBRO ANIMAL HEALTH CORP-A Common Stock 71742Q106   27 2,357 SH   SOLE   2,357 0 0
OVID THERAPEUTICS INC Common Stock 690469101   26 8,178 SH   SOLE   8,178 0 0
VERALTO CORP Common Stock 92338C103   24 290 SH   SOLE   290 0 0
CHARLES RIVER LABORATORIES Common Stock 159864107   21 89 SH   SOLE   89 0 0
REPLIGEN CORP Common Stock 759916109   21 115 SH   SOLE   115 0 0
EDWARDS LIFESCIENCES CORP Common Stock 28176E108   20 256 SH   SOLE   256 0 0
IQVIA HOLDINGS INC Common Stock 46266C105   19 84 SH   SOLE   84 0 0
BLUEBIRD BIO INC Common Stock 09609G100   17 12,647 SH   SOLE   12,647 0 0
VENTYX BIOSCIENCES INC Common Stock 92332V107   17 6,832 SH   SOLE   6,832 0 0
EXACT SCIENCES CORP Common Stock 30063P105   16 216 SH   SOLE   216 0 0
ESTEE LAUDER COMPANIES-CL A Common Stock 518439104   14 99 SH   SOLE   99 0 0
ACLARIS THERAPEUTICS INC Common Stock 00461U105   9 8,196 SH   SOLE   8,196 0 0
RENEO PHARMACEUTICALS INC Common Stock 75974E103   6 3,856 SH   SOLE   3,856 0 0
TEXAS ROADHOUSE INC Common Stock 882681109   5 44 SH   SOLE   44 0 0
KROGER CO Common Stock 501044101   3 60 SH   SOLE   60 0 0
HERSHEY CO/THE Common Stock 427866108   2 10 SH   SOLE   10 0 0
JD.COM INC-ADR ADR 47215P106   2 64 SH   SOLE   64 0 0
NIU TECHNOLOGIES-SPONS ADR ADR 65481N100   2 1,000 SH   SOLE   1,000 0 0
RALPH LAUREN CORP Common Stock 751212101   2 16 SH   SOLE   16 0 0
CAPRI HOLDINGS LTD Common Stock G1890L107   0 8 SH   SOLE   8 0 0
FARFETCH LTD-CLASS A Common Stock 30744W107   0 7,800 SH   SOLE   7,800 0 0