X0508 4 2023-08-24 0 0001906324 QuidelOrtho Corp QDEL 0001406652 BRYANT DOUGLAS C 9975 SUMMERS RIDGE ROAD SAN DIEGO CA 92121 1 1 0 0 President & CEO 0 Common Stock 2023-08-24 4 A 0 1461 0.00 A 536295 D Common Stock 2023-08-24 4 F 0 725 78.33 D 535570 D Restricted Stock Units 2023-08-24 4 M 0 1461 0.00 D Common Stock 1461 0 D Reflects release of restricted stock units that were previously reported on a Form 4. The amount of shares beneficially owned following this transaction includes an additional 291 shares due to the Reporting Person's purchase of shares pursuant to the Issuer's Employee Stock Purchase Plan. Disposition of shares, as set forth above, was in connection with the Issuer's withholding of common shares to satisfy tax withholding obligations related to the issuance of common shares upon release of restricted stock units. Each restricted stock unit represents the right to receive one share of QuidelOrtho Corporation common stock. 1,461 shares vested on August 24, 2023. /s/ Phillip S. Askim, attorney-in-fact for Douglas C. Bryant 2023-08-28