X0407 4 2023-06-01 0 0001906324 QuidelOrtho Corp QDEL 0001839432 Iskra Michael S. 9975 SUMMERS RIDGE ROAD SAN DIEGO CA 92121 0 1 0 0 EVP & CCO 0 Common Stock 2023-06-01 4 A 0 3594 0.00 A 12746 D Common Stock 2023-06-01 4 F 0 1839 85.65 D 10907 D Restricted Stock Units 2023-06-01 4 M 0 3594 0.00 D Common Stock 3594 7188 D Reflects release of restricted stock units that were previously reported on a Form 4. Disposition of shares, as set forth above, was in connection with the Issuer's withholding of common shares to satisfy tax withholding obligations related to the issuance of common shares upon release of restricted stock units. Each restricted stock unit represents the right to receive one share of QuidelOrtho Corporation common stock. 3,594 shares vested on June 1, 2023; the remaining 7,188 shares will vest in equal installments on June 1, 2024 and June 1, 2025. /s/ Phillip S. Askim, attorney-in-fact for Michael S. Iskra 2023-06-05