X0306 4 2022-11-08 0 0001906324 QuidelOrtho Corp QDEL 0001833942 Hodges Michelle A. 9975 SUMMERS RIDGE ROAD SAN DIEGO CA 92121 0 1 0 0 SVP, General Counsel Common Stock 2022-11-08 4 A 0 3970 0.00 A 4874 D Common Stock 2022-11-08 4 F 0 1969 87.69 D 2905 D Restricted Stock Units 2022-11-08 4 M 0 3970 0.00 D Common Stock 3970 7940 D Reflects release of restricted stock units that were previously reported on a Form 4. Disposition of shares, as set forth above, was in connection with the Issuer's withholding of common shares to satisfy tax withholding obligations related to the issuance of common shares upon release of restricted stock units. Each restricted stock unit represents the right to receive one share of QuidelOrtho Corporation common stock. 3,970 shares vested on November 8, 2022; the remaining 7,940 shares will vest in equal installments on November 8, 2023 and November 8, 2024. /s/ Phillip S. Askim, attorney-in-fact for Michelle A. Hodges 2022-11-10