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Consolidated Statements of Profit or Loss and Other Comprehensive Income or Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Profit or loss [abstract]      
Product revenue $ 48,699 $ 24,836 $ 0
License and other revenue 42,735 58,193 36,772
Other income 1,948 1,988 2,912
Cost of product revenue (160,856) (64,095) 0
Research and development expenses (210,827) (180,622) (191,006)
General and administrative expenses (76,559) (186,742) (84,134)
Operating loss (354,860) (346,442) (235,456)
Share of net loss of joint venture (7,153) (2,590) (2,418)
Impairment loss on investment in joint venture 21,519 0 0
Finance income 4,823 2,549 51,568
Finance costs (267,157) (188,419) (117,361)
Exchange rate differences (5,183) 10,566 2,681
(Loss) / gain on extinguishment of financial liabilities 0 (27,311) 151,788
Non-operating (loss) / profit (296,189) (205,205) 86,258
Loss before taxes (651,049) (551,647) (149,198)
Income tax benefit 99,318 38,067 47,694
Loss for the year (551,731) (513,580) (101,504)
Item that will be reclassified to profit or loss in subsequent periods:      
Exchange rate differences on translation of foreign operations (86) (6,111) (305)
Total comprehensive loss $ (551,817) $ (519,691) $ (101,809)
Loss per share      
Basic (in dollars per share) $ (2.43) $ (2.60) $ (0.92)
Diluted (in dollars per share) $ (2.43) $ (2.60) $ (0.92)