<SEC-DOCUMENT>0001894562-25-000024-index.html : 20250519
<SEC-HEADER>0001894562-25-000024.hdr.sgml : 20250519
<ACCEPTANCE-DATETIME>20250519194533
ACCESSION NUMBER:		0001894562-25-000024
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		3
CONFORMED PERIOD OF REPORT:	20250519
FILED AS OF DATE:		20250519
DATE AS OF CHANGE:		20250519

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Marrazzo Jeffrey D
		CENTRAL INDEX KEY:			0001631262
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-41536
		FILM NUMBER:		25965797

	MAIL ADDRESS:	
		STREET 1:		3737 MARKET STREET
		STREET 2:		SUITE 1300
		CITY:			PHILADELPHIA
		STATE:			PA
		ZIP:			19104

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Prime Medicine, Inc.
		CENTRAL INDEX KEY:			0001894562
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		60 FIRST ST.
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02141
		BUSINESS PHONE:		617-465-0013

	MAIL ADDRESS:	
		STREET 1:		60 FIRST ST.
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02141
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>wk-form4_1747698326.xml
<DESCRIPTION>FORM 4
<TEXT>
Document 1 - file: wk-form4_1747698326.html

Document 1 - RAW XML: wk-form4_1747698326.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>prime_medicinex-xpowerxo.htm
<DESCRIPTION>EX-24
<TEXT>
Document 2 - file: prime_medicinex-xpowerxo.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>prime_medicinex-xpowerxo001.jpg
<TEXT>
Document 3 - file: prime_medicinex-xpowerxo001.jpg

</DOCUMENT>
</SEC-DOCUMENT>