<SEC-DOCUMENT>0001628280-23-013832-index.html : 20230428
<SEC-HEADER>0001628280-23-013832.hdr.sgml : 20230428
<ACCEPTANCE-DATETIME>20230428085115
ACCESSION NUMBER:		0001628280-23-013832
CONFORMED SUBMISSION TYPE:	ARS
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20221231
FILED AS OF DATE:		20230428
DATE AS OF CHANGE:		20230428
EFFECTIVENESS DATE:		20230428

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Prime Medicine, Inc.
		CENTRAL INDEX KEY:			0001894562
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		ARS
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-41536
		FILM NUMBER:		23860622

	BUSINESS ADDRESS:	
		STREET 1:		21 ERIE ST.
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139
		BUSINESS PHONE:		617-465-0013

	MAIL ADDRESS:	
		STREET 1:		21 ERIE ST.
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139
</SEC-HEADER>
<DOCUMENT>
<TYPE>ARS
<SEQUENCE>1
<FILENAME>a2022annualreportforshareh.pdf
<DESCRIPTION>ARS
<TEXT>
Document 1 - file: a2022annualreportforshareh.pdf

</DOCUMENT>
</SEC-DOCUMENT>