X0306 4 2021-11-12 0 0001680367 Shattuck Labs, Inc. STTK 0001894232 Brownstein Carrie C/O SHATTUCK LABS, INC. 500 W. 5TH STREET, SUITE 1200 AUSTIN TX 78701 1 0 0 0 Stock Option (Right to Buy) 19.27 2021-11-12 4 A 0 10467 0.00 A 2031-11-12 Common Stock 10467 10467 D This option represents a right to purchase a total of 10,467 shares of the Issuer's common stock, which will vest in three equal annual installments on each of the first three anniversaries of October 22, 2021, subject to the Reporting Person's continued service to the Issuer. /s/ Erin Ator Thomson, Attorney-in-Fact for Carrie Brownstein 2021-11-17