The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AbbVie Inc. Common 00287Y109   1,055,352 5,037 SH   DFND 1 5,037 0 0
AllianceBernstein Holding L.P. Common 01881G106   1,838,880 48,000 SH   DFND 1 48,000 0 0
Alphabet Inc CL A Common 02079k305   46,392 300 SH   DFND 1 300 0 0
Alphabet Inc-Cl C Common 02079K107   34,371 220 SH   DFND 1 220 0 0
Alphabet Inc-Cl C Common 02079K107   17,497,760 112,000 SH   DFND 1 112,000 0 0
Amazon.com Inc. Common 023135106   57,078 300 SH   DFND 1 300 0 0
Apollo Global Management, Inc. Common 03769M106   30,811,500 225,000 SH   DFND 1 225,000 0 0
Apple Inc. Common 037833100   553,992 2,494 SH   DFND 1 2,494 0 0
Arc Resources Ltd. Common 00208D408   22,289 1,110 SH   DFND 1 1,110 0 0
Arcellx Inc Common 03940c100   984,000 15,000 SH   DFND 1 15,000 0 0
Arcus Biosciences, Inc. Common 03969F109   94,200 12,000 SH   DFND 1 12,000 0 0
Ardelyx, Inc. Common 039697107   2,424,592 493,807 SH   DFND 1 493,807 0 0
AtriCure, Inc. Common 04963C209   794,241 24,620 SH   DFND 1 24,620 0 0
aTyr Pharma, Inc. Common 002120202   674,689 223,407 SH   DFND 1 223,407 0 0
Autolus Therapeutics PLC Common 05280R100   651,000 420,000 SH   DFND 1 420,000 0 0
Avadel Pharmaceuticals plc Common G29687103   3,335,580 426,000 SH   DFND 1 426,000 0 0
BioCryst Pharmaceuticals, Inc. Common 09058V103   3,450,000 460,000 SH   DFND 1 460,000 0 0
Blackstone Group LP Common 09260d107   29,354 210 SH   DFND 1 210 0 0
Bristol-Myers Squibb Company Common 110122108   1,158,810 19,000 SH   DFND 1 19,000 0 0
Broadcom, Inc. Common 11135F101   118,875 710 SH   DFND 1 710 0 0
Calumet, Inc. Common 131428104   41,808,420 3,297,194 SH   DFND 1 3,297,194 0 0
Canadian Natural Resources Limited Common 136385101   517,440 16,800 SH   DFND 1 16,800 0 0
Catalyst Pharmaceuticals, Inc. Common 14888U101   5,141,000 212,000 SH   DFND 1 212,000 0 0
Coca-Cola Co. Common 191216100   143,240 2,000 SH   DFND 1 2,000 0 0
Cogent Biosciences Inc. Common 19240Q201   1,277,679 213,302 SH   DFND 1 213,302 0 0
Collegium Pharmaceutical, Inc. Common 19459J104   1,148,419 38,473 SH   DFND 1 38,473 0 0
Corteva, Inc. Common 22052L104   695,439 11,051 SH   DFND 1 11,051 0 0
CSX Corporation Common 126408103   2,060,100 70,000 SH   DFND 1 70,000 0 0
Cybin Inc Common 23256X407   424,019 66,880 SH   DFND 1 66,880 0 0
Danaher Corporation Common 235851102   36,900 180 SH   DFND 1 180 0 0
DocGo, Inc. Common 256086109   8,107,044 3,070,850 SH   DFND 1 3,070,850 0 0
Dow Inc. Common 260557103   42,114 1,206 SH   DFND 1 1,206 0 0
DuPont de Nemours, Inc. Common 26614N102   703,336 9,418 SH   DFND 1 9,418 0 0
Eastern Bankshares Inc Common 27627N105   82,000 5,000 SH   DFND 1 5,000 0 0
Eli Lilly & Co. Common 532457108   247,773 300 SH   DFND 1 300 0 0
Enstar Group Limited Common G3075P101   2,492,850 7,500 SH   DFND 1 7,500 0 0
FS Bancorp, Inc. Common 30263Y104   55,495 1,460 SH   DFND 1 1,460 0 0
FS KKR Capital Corp. Common 302635206   60,231 2,875 SH   DFND 1 2,875 0 0
GE HealthCare Technologies Inc Common 36266G107   4,035 50 SH   DFND 1 50 0 0
Immunovant Inc. Common 45258J102   383,551 22,443 SH   DFND 1 22,443 0 0
Inozyme Pharma, Inc. Common 45790W108   606,246 666,204 SH   DFND 1 666,204 0 0
International Business Machines Common 459200101   532,630 2,142 SH   DFND 1 2,142 0 0
International Game Technology PLC Common G4863A108   40,650 2,500 SH   DFND 1 2,500 0 0
iShares Russell Mid-Cap Growth Common 464287481   81,656 695 SH   DFND 1 695 0 0
Janus Henderson AAA CLO ETF Common 47103U845   8,008,732 157,932 SH   DFND 1 157,932 0 0
Janus Henderson AAA CLO ETF Common 47103U845   19,971,170 393,831 SH   DFND 1 393,831 0 0
Johnson & Johnson Common 478160104   152,905 922 SH   DFND 1 922 0 0
JPMorgan Chase & Co. Common 46625H100   5,147,620 20,985 SH   DFND 1 20,985 0 0
Kimberly-Clark Corporation Common 494368103   853,320 6,000 SH   DFND 1 6,000 0 0
Kyndryl Holdings Inc. Common 50155Q100   13,439 428 SH   DFND 1 428 0 0
Legacy Housing Corporation Common 52472M101   163,930 6,500 SH   DFND 1 6,500 0 0
MeiraGTx Holdings plc Common G59665102   847,568 125,010 SH   DFND 1 125,010 0 0
Mereo BioPharm Group PLC Common 589492107   718,508 319,337 SH   DFND 1 319,337 0 0
Microsoft Corporation Common 594918104   600,624 1,600 SH   DFND 1 1,600 0 0
Mondelez International Inc. Common 609207105   610,650 9,000 SH   DFND 1 9,000 0 0
Myriad Genetics, Inc. Common 62855J104   1,419,200 160,000 SH   DFND 1 160,000 0 0
Nvidia Corp Common 67066G104   138,726 1,280 SH   DFND 1 1,280 0 0
Occidental Petroleum Corporation Common 674599105   23,150 469 SH   DFND 1 469 0 0
Occidential Pertro Wts exp. 8/3/27 Common 674599105   4,268 194 SH   DFND 1 194 0 0
OmniAB, Inc. Common 68218J103   2,357,606 982,336 SH   DFND 1 982,336 0 0
Pfizer Inc. Common 717081103   2,142,168 84,537 SH   DFND 1 84,537 0 0
Pfizer Inc. Common 717081103   4,307,800 170,000 SH   DFND 1 170,000 0 0
Protagonist Therapeutics, Inc Common 74366E102   3,675,360 76,000 SH   DFND 1 76,000 0 0
Quanta Services, Inc. Common 74762E102   44,736 176 SH   DFND 1 176 0 0
Regeneron Pharmaceuticals, Inc. Common 75886F107   1,268,460 2,000 SH   DFND 1 2,000 0 0
Ryman Hospitality Properties, Inc. Common 78377T107   1,097,280 12,000 SH   DFND 1 12,000 0 0
Salesforce, Inc. Common 79466L302   20,664 77 SH   DFND 1 77 0 0
Solid Bioscience Inc. Common 83422E204   488,400 132,000 SH   DFND 1 132,000 0 0
SPDR S&P Biotech ETF Common 78464A870   1,106,447 13,643 SH   DFND 1 13,643 0 0
Starwood Property Trust, Inc. Common 85571B105   7,908 400 SH   DFND 1 400 0 0
Syndax Pharmaceutical, Inc. Common 87164F105   1,572,480 128,000 SH   DFND 1 128,000 0 0
Tectonic Therapeutic, Inc. Common 878972108   708,400 40,000 SH   DFND 1 40,000 0 0
The Invesco AAA Floating Rate Note ETF Common 46090A721   1,797,096 70,502 SH   DFND 1 70,502 0 0
The Panagram AAA CLO ETF Common 81752T486   147,091 5,766 SH   DFND 1 5,766 0 0
The Panagram BBB-B CLO ETF Common 81752T528   1,270,232 47,807 SH   DFND 1 47,807 0 0
Thermo Fisher Scientific, Inc. Common 883556102   22,392 45 SH   DFND 1 45 0 0
TotalEnergies SE - ADR Common 89151E109   77,628 1,200 SH   DFND 1 1,200 0 0
Travere Therapeutics, Inc. Common 89422G107   4,085,760 228,000 SH   DFND 1 228,000 0 0
Ultragenyx Pharmaceutical Inc. Common 90400D108   1,738,080 48,000 SH   DFND 1 48,000 0 0
United Healthcare Corp. Common 91324p102   29,854 57 SH   DFND 1 57 0 0
United Rental, Inc. Common 911363109   48,883 78 SH   DFND 1 78 0 0
Vera Therapeutics, Inc. Common 92337R101   240,200 10,000 SH   DFND 1 10,000 0 0
Verona Pharma PLC. Common 925050106   5,587,120 88,000 SH   DFND 1 88,000 0 0
Viridian Therapeutics, Inc. Common 92790C104   404,400 30,000 SH   DFND 1 30,000 0 0
Wabtec Corporation Common 929740108   1,088 6 SH   DFND 1 6 0 0
Wave Life Science Ltd. Common Y95308105   80,800 10,000 SH   DFND 1 10,000 0 0
Xenon Pharmaceuticals Inc. Common 98420N105   532,304 15,866 SH   DFND 1 15,866 0 0
Xeris Biopharma Holdings, Inc. Common 98422E103   6,093,900 1,110,000 SH   DFND 1 1,110,000 0 0