EX-99.2 3 ea184837ex99-2_clearmind.htm MANAGEMENT'S DISCUSSION AND ANALYSIS FOR THE FOR THE THREE AND NINE MONTHS ENDED JULY 31, 2023

Exhibit 99.2

 

 

 

 

 

 

 

 

 

 

CLEARMIND MEDICINE INC.

 

MANAGEMENT’S DISCUSSION AND ANALYSIS 

 

For the Three and Nine Months Ended July 31, 2023

 

(Expressed in United States Dollars)

 

(Unaudited)

 

 

 

 

 

 

 

 

 

 

 

 

 

CLEARMIND MEDICINE INC.

Management’s Discussion and Analysis

For the Three and Nine Months Ended July 31, 2023

 

This Management’s Discussion and Analysis (“MD&A”) of Clearmind Medicine Inc. (“Clearmind” or the “Company”), prepared as of September 13, 2023, should be read in conjunction with the unaudited condensed interim consolidated financial statements and the notes thereto for the three and nine months ended July 31, 2023, which were prepared in accordance with International Financial Reporting Standards (“IFRS”). All amounts are expressed in United States dollars unless otherwise indicated.

 

Additional information about the Company is available on SEDAR at www.sedar.com.

 

Cautionary Statement Regarding Forward-Looking Information

 

This MD&A may contain “forward-looking statements” which reflect the Company’s current expectations regarding future results of operations, performance and achievements of the Company. The Company has tried, wherever possible, to identify these forward-looking statements by, among other things, using words such as “anticipate,” “believe,” “estimate,” “expect” and similar expressions. The statements reflect the current beliefs of the management of the Company, and are based on currently available information. Accordingly, these statements are subject to known and unknown risks, uncertainties and other factors, which could cause the actual results, performance, or achievements of the Company to differ materially from those expressed in, or implied by, these statements.

 

The Company undertakes no obligation to publicly update or review the forward-looking statements whether as a result of new information, future events or otherwise.

 

Historical results of operations and trends that may be inferred from the following discussions and analysis may not necessarily indicate future results from operations.

 

Description of Business and Company Overview

 

Corporate Information

 

The Company was incorporated under the name Cyntar Ventures Inc. on July 18, 2017, pursuant to the provisions of the Business Corporations Act (British Columbia). On March 24, 2021, the name of the Company was changed to Clearmind Medicine Inc. The Company’s principal executive offices are located at 101 – 1220 W. 6th Ave, Vancouver, BC V6H1A5 and its operational offices are located at 20 Rahul Wallenberg, Tel Aviv, Israel.

 

Originally, the Company operated as a mineral resource exploration operations company. In September 2020, the Company announced a shift of the focus of the business to the development of innovative psychedelic therapies. This process involved the acquisition of all rights, title and interests in several patent applications for the treatment of alcohol use disorders, or AUD, and various other non-controlled binge behaviors. As part of this process, the Company announced a Change of Business, or COB listing, on the CSE. The COB became effective in November 2020. In May 2021, the Company completed all of the requirements of the CSE for a COB listing. The Company’s common shares trade on the Canadian Securities Exchange under the symbol “CMND”.

 

On September 30, 2022, the Company’s Board of Directors approved a 1-for-30 reverse split of its issued and outstanding ordinary shares, effective as of September 30, 2022, pursuant to which holders of the Company’s ordinary shares received 0.0333 of an ordinary share for every one ordinary share.

 

Significant developments during the period

 

On November 14, 2022, the Company completed a public offering for aggregate gross proceeds of US$7.5 million and up listing to the Nasdaq Capital Market (“Nasdaq”). Net proceeds of the offering were $6.4 million. As a result, the Company also trades under the symbol “CMND” on the Nasdaq.

 

 

 

 

CLEARMIND MEDICINE INC.

Management’s Discussion and Analysis

For the Three and Nine Months Ended July 31, 2023

 

In March 2023, the Company announced that it had submitted an IND application with the FDA, requesting approval to initiate our first-in-human Phase I/IIa clinical trial with CMND-100 in patients suffering from AUD. Subsequently, in May 2023, the Company initiated the CM-CMND-001 clinical trial in both Israel and the United States.

 

The Israeli study is be led by Prof. Mark Weiser, M.D., head of the Psychiatric Division at the Sheba Medical Center in the Tel Aviv suburb of Ramat Gan. Our first U.S. site for the CM-CMND-001 clinical trial is at the Yale School of Medicine’s Department of Psychiatry. The site is led by Anahita Bassir Nia, MD, a specialist in substance abuse, including alcohol abuse. In addition, the Company intends to open a second site in the United States for the CM-CMND-001 clinical trial.

 

The CM-CMND-001 clinical trial is designed to be a multinational, multi-center, Phase I/IIa single- and multiple-dose tolerability, safety and pharmacokinetic study in healthy volunteers and AUD subjects.

 

In the Phase I part of the trial of the clinical trial, oral capsules (CMND-100) will be administered once to healthy volunteers and AUD subjects respectively with single, ascending dose of CMND-100, for evaluation of tolerability, safety and pharmacokinetics/ pharmacodynamics. or PK/PD. In the Phase IIa part of the clinical trial which is a randomized, double-blind, placebo-controlled part, CMND-100 oral capsules will be administered once daily for ten consecutive days to healthy volunteers and AUD subjects for evaluation of safety, PK/PD and preliminary efficacy. The patients will report their drinking patterns and craving for alcohol (and cigarettes) during the clinical trial period.

 

The primary end-point of the trial is to find the tolerable dose and characterize the safety, tolerability and PK/PD of single and repeated doses of CMND-100 in healthy subjects and in those with AUD. The secondary end-point is to evaluate preliminary efficacy of CMND-100 in reduction of drinking patterns and craving in individuals with moderate-to-severe AUD.

 

On April 6, 2023, the Company completed an underwritten public offering for aggregate gross proceeds of US$3.5 million. Net proceeds of the offering were $2.9 million (“April 2023 Public Offering”)

 

Company Overview

 

The Company is a pre-clinical pharmaceutical company approaching phase 1 clinical trials, that develops novel psychedelic medicines to solve widespread, yet under-served, health problems. The Company’s goal is to develop and provide a new type of treatment for mental health disorders, including AUD, binge drinking and eating disorders, where there is significant unmet need and lack of innovation. The Company sees psychedelic therapies, which previously may have been overlooked or underused, as the future of treatment for a variety of indications. The Company believes that its solution for AUD can help solve one of the world’s biggest health problems, which costs the United States alone roughly $250 billion each year.

 

The Company’s flagship treatment and focus for the short term is on AUD, which is incredibly common. It varies from mild to excessive and describes a person’s inability to restrict their alcohol consumption, despite negative social, occupational, or health consequences. Alcohol consumption contributes to 3 million deaths each year globally and is the third most common preventable cause of death in the United States. Apart from potentially changing people’s lives, the Company believes that the Company’s treatment could potentially reduce the amount currently being spent on the consequences of AUD in the United States, Europe, India, China and other countries around the world. The Company also believes that its treatment may address binge drinking. 95,000 people die every year in the United States alone due to binge drinking.

 

2

 

 

CLEARMIND MEDICINE INC.

Management’s Discussion and Analysis

For the Three and Nine Months Ended July 31, 2023

 

The Company has completed a series of pre-clinical IND enabling studies in the United States and China that are required before the Company can study its compound for the first time in humans. These studies include pharmacokinetic and toxicological studies in rats and dogs in order to assess the safety profile of the Company’s compound and characterization of the drug metabolism. The Company has conducted several metabolism studies designed to better understand the way 5-Methoxy-2-aminoindane, or MEAI, is digested in several species. In addition, the Company has conducted a pre-clinical animal model of AUD to characterize the effect of MEAI on alcohol consumption. This study involved testing the effect of MEAI’s ability to curb alcohol cravings after exposing mice to prolonged alcohol consumption over a short period, mimicking binge alcohol consumption in humans.

 

The Company intends to submit the Company’s IND request and to initiate the Phase I/IIa clinical study in the first quarter of 2023. As part of this strategy, the Company had a pre-IND meeting with the U.S. Food and Drug Administration, or FDA, in May 2022. The Company plans to submit applications to conduct the Phase I/IIa study in Europe, the United States and Israel. Upon completion of the Phase I/IIa studies, if successful, the Company will be required to conduct additional clinical trials subject to securing additional financing.

 

Research and development work

 

In addition to the Company’s research programs on the uses of MEAI, the Company has plans to conduct 12 other research programs on different molecules, which are to be led by the Company’s highly skilled, focused team, with deep expertise in their respective fields, several of whom have taken products from the discovery phase to clinical trials in the United States in their previous respective roles, as well as key members of the Company’s scientific advisory board who have participated in numerous clinical trials in the areas of alcoholism and addiction.

 

These 12 additional drug programs can be separated into two categories. Nine of these programs are in the pre-discovery phase, and are primarily aimed at discovering innovative molecules designed for the treatment of mental health diseases such as depression, anxiety and post-traumatic stress disorder, or PTSD. Of the remaining three of these programs which are all in the discovery phase, one is aimed at the treatment of depression and treatment resistant depression, or TRD, while the other two are aimed at studying substances that can replicate the effects of 3,4-methylenedioxymethamphetamine, or MDMA, for therapeutic purposes.

 

In the Company’s research program aimed at treating depression and TRD, the Company has been studying the effects of administering 2-fluorodeschloroketamine, or 2-FDCK. The Company investigated 2-FDCK in a pre-clinical proof-of-concept study. In the Company’s two research programs aimed at finding substances that can be utilized for the same therapeutic purposes as MDMA, the Company will be studying 1-(Benzofuran-5-yl)-N-methylpropan-2-amine, or 5-MAPB and 1-Benzofuran-6-yl propan-2-amine, or 6-APB. The Company believes these treatments may be beneficial for fail-safes for MDMA based on a September 2016 article from Naunyn-Schmiedeberg’s Archives of Pharmacology, which reported the receptor binding profiles of 5-MAPB and 6-APB are different enough from MDMA to effectively perform a substitute role in the therapy while being similar enough so as not to have to change the therapeutic protocol.

 

3

 

 

CLEARMIND MEDICINE INC.

Management’s Discussion and Analysis

For the Three and Nine Months Ended July 31, 2023

 

Strategy

 

With respect to the Company’s AUD programs, the Company developed MEAI as a new chemical entity (NCE) drug candidate. The Company intends to seek regulatory approval through the FDA’s 505(b)(1) regulatory path. The FDA’s 505(b)(1) regulatory path is typically used for novel drugs that have not previously been studied or approved, and drug development pursuant to this path requires drug developers to conduct all studies needed to demonstrate the safety and efficacy of the drug. Given its nature, this type of submission requires extensive research, including both clinical and nonclinical studies, to prove the product’s safety and efficacy for the indication being sought.

 

Pursuant to the Company’s pre-IND meeting correspondence with the FDA, the FDA informed the Company that the Phase I portion of the Company’s Phase I/IIa study could not include only AUD patients (i.e., the Company’s target population). Accordingly, at the pre-IND meeting, the Company discussed a hybrid model for the Phase I portion of the study, where the Company would study both healthy volunteers and AUD patients, and the FDA did not rule this out as a possibility. While the Company cannot guarantee that the FDA will approve the Company’s request, if approved, such special accommodation would allow the Company’s to start the first in-human study with the target population rather than with healthy volunteers. If the FDA grants the Company the ability to use the hybrid model that includes AUD patients, the Company’s timeline for the clinical development of MEAI could be accelerated as it will potentially allow the Company’s to submit only one IND application, IRB application and one set of study reports for both Phase I and Phase IIa of the Company’s clinical trial. Furthermore, this model allows the Company to reach the Company’s target population quicker, hence getting more substantial safety data on the Company’s target population at an earlier stage.

 

Prior Use of Proceeds Disclosure

 

The table below describe the difference between the Company’s anticipated use of proceeds from public offerings completed since November 2022, as disclosed in previous news releases. The table shows the amounts actually spent for the period from November 1, 2022 through to July 31, 2023, The Company notes the below variances do not have a material impact on the Company’s ability to achieve its business objectives and milestones.

 

Use of Available Funds   Disclosure
Regarding
Use of
Proceeds
(USD)
  Spent
through to
July 31,
2023
(USD)
November 2022 public offering:        
to advance the formulation and clinical development efforts in our MEAI patented compounds;   1.5 million   0.93 million
to complete the pre-IND enabling studies and IND submission   1.0 million   0.71 million
to complete planned Phase I/IIa studies   3.5 million   0.34 million
the remainder for working capital and general corporate purposes and possible in-licensing of intellectual property for new product candidates   0.4 million   0.4 million
April 2023 Public Offering        
general corporate purposes, which may include operating expenses, research and development, including clinical and pre-clinical testing of our product candidates, working capital, future acquisitions and general capital expenditures   2.9 million   2.9 million

 

 

 

4

 

 

CLEARMIND MEDICINE INC.

Management’s Discussion and Analysis

For the Three and Nine Months Ended July 31, 2023

 

Selected Financial Information

 

The following financial data prepared in accordance with IFRS in United States dollars is presented for the three and nine month periods ended July 31, 2023 and 2022.

 

   Three months ended   Nine months ended 
   July 31,   July 31, 
   2023   2022   2023   2022 
Operating expenses                
General and administrative  $838,925   $1,025,554   $3,422,798   $3,301,755 
Research and development, net   263,954    325,321    1,169,156    1,796,916 
Total operating expenses   1,102,879    1,350,875    4,591,954    5,098,671 
                     
Finance expenses                    
                     
Changes in fair value of warrants (Note 5)   482,331        121,774     
Unrealized loss on short-term investment   (12,222)   (181,807)   (70,971)   (277,619)
Foreign exchange gain (loss)   33,645    60,797    (61,711)   46,727 
Finance income (expense), net   17,307    (11,127)   41,288     
Total finance incomes (expenses)   521,061    (132,137)   30,380    (230,892)
                     
Other income                    
Dividend received           16,555     
Total other income           16,555     
                     
Loss before taxes   (581,818)   (1,483,012)   (4,545,019)   (5,329,563)
Tax expenses   6,631        (6,019)    
Net Loss and Comprehensive loss  $(575,187)  $(1,483,012)  $(4,551,038)  $(5,329,563)
Loss per share (*), basic and diluted  $(0.08)  $(1.12)  $(1.04)  $(4.16)
Weighted average number of shares (*) for the purposes of basic and diluted loss per share   7,088,852    1,319,745    4,384,905    1,279,977 

 

Three-month period ended July 31, 2023, compared to the three-month period ended July 31, 2022

 

Research Costs

 

Research costs are comprised primarily of (i) Salaries and wages to Company employees at and (ii) pre-clinical trials.

 

For the three-month period ended July 31, 2023, research costs amounted to $263,954 as compared to $325,321 for the three-month period ended July 31, 2022.

 

General and Administrative Expenses

 

For the three-month period ended July 31, 2023, general and administrative expenses amounted to $838,925 as compared to $1,025,554 for the three-month period ended July 31, 2022.

 

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CLEARMIND MEDICINE INC.

Management’s Discussion and Analysis

For the Three and Nine Months Ended July 31, 2023

 

Finance incomes (expenses)

 

For the three-month period ended July 31, 2023, financial incomes amounted to $521,061 as compared to financial expenses of ($132,137) for the three-month period ended July 31, 2022. The financial incomes during the three-month period ended July 31, 2023 consist of change in warrant liability of $482,331, foreign exchange gain of $33,645, unrealized loss on short-term investment of $12,222 and finance income, net of $17,307.

 

Loss for the period

 

The Company reported a loss for the three-month period ended July 31, 2023 of $575,187 as compared to a loss of $1,483,012 for the three-month period ended July 31, 2022.

 

Nine-month period ended July 31, 2023, compared to the nine-month period ended July 31, 2022

 

Research Costs

 

Research costs are comprised primarily of (i) Salaries and wages to Company employees at and (ii) pre-clinical trials.

 

For the nine-month period ended July 31, 2023, research costs amounted to $1,169,156 as compared to $1,796,916 for the nine-month period ended July 31, 2022.

 

General and Administrative Expenses

 

For the nine-month period ended July 31, 2023, general and administrative expenses amounted to $3,422,798 as compared to $3,301,755 for the nine-month period ended July 31, 2022. The amount incurred in 2023 is consistent with the amount spent in 2022.

 

Finance incomes (expenses)

 

For the nine-month period ended July 31, 2023, financial incomes amounted to $30,380 as compared to financial expenses of ($230,892) for the nine-month period ended July 31, 2022. The financial expenses during the nine-month period ended July 31, 2023 consist of change in warrant liability of $121,774, foreign exchange loss of $61,711, unrealized loss on short-term investment of $70,971 and finance income, net of $41,288

 

Loss for the period

 

The Company reported a loss for the nine-month period ended July 31, 2023 of 4,551,038 as compared to a loss of $5,329,563 for the nine-month period ended July 31, 2022.

 

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CLEARMIND MEDICINE INC.

Management’s Discussion and Analysis

For the Three and Nine Months Ended July 31, 2023

 

Financial Summary of Quarterly Results

 

The following is a summary of the Company’s financial results for the eight most recently completed quarters.

 

   July 31,
2023
   April 30,
2023
   January 31,
2023
   October 31,
2022
 
                 
Total revenues  $      –   $     –   $   $ 
Net loss   (575,187)   (2,076,382)   (1,869,996)   (1,554,178)
Net loss per share, basic and diluted   (0.08)   (0.55)   (0.79)   (1.22)

 

   July 31,
2022
   April 30,
2022
   January 31,
2022
   October 31,
2021
 
                 
Total revenues  $   $   $   $ 
Net loss   (1,483,012)   (2,325,785)   (1,531,895)   (1,853,101)
Net loss per share, basic and diluted   (1.12)   (1.78)   (1.22)   (1.98)

 

Factors causing significant variations in quarterly results are as follows:

 

The increase in loss for the quarter ended October 31, 2021, was primarily due to an increase in share-based compensation that relates to the grant of 111,889 stock options and 6,667 restricted share units during the quarter, and an increase in research and development.

 

The decrease in loss for the quarter ended January 31, 2022, was primarily due to a decrease in share-based compensation.

 

The increase in loss for the quarter ended April 30, 2022, was primarily due to an increase in research and development.

 

The decrease in loss for the quarter ended July 31, 2022, was primarily due to a decrease in research and development.

 

The increase in loss for the quarter ended October 31, 2022, was primarily due to an increase in research and development.

 

The increase in loss for the quarter ended January 31, 2023, was primarily due to an increase in general and administrative.

 

  The increase in loss for the quarter ended April 30, 2023, was primarily due to an increase in financial expenses relating to the change in fair value of the warrant liability of $360,557.
     
  The decrease in loss for the quarter ended July 31, 2023, was primarily due to a gain on the revaluation of the total warrant liability of $482,331.

 

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CLEARMIND MEDICINE INC.

Management’s Discussion and Analysis

For the Three and Nine Months Ended July 31, 2023

 

Liquidity and Capital Resources

 

As of July 31, 2023, the Company had cash on hand of $3,847,259 and positive working capital of $2,695,028, compared to $128,777 and negative working capital of $1,497,720 as of October 31, 2022, respectively. During the nine-month period ended July 31, 2023, the Company’s overall position of cash increased by $3,718,482 from the year ended October 31, 2022. This increase in cash can be attributed to the following:

 

The Company’s net cash used in operating activities during the nine-month period ended July 31, 2023, was $5,548,304 as compared to $3,518,605 for the nine-month period ended July 31, 2022. This increase is mostly due to increase in prepaid expenses and decreases in accounts payable and accrued liabilities.

 

Net cash provided by Investing activities for the nine -month period ended July 31, 2023, was $7,686 as compared to $nil for the nine-month period ended July 31, 2022.

 

Net cash provided by financing activities for the nine -month period ended July 31, 2023, was $9,259,126 as compared to $580,721 for the nine-month period ended July 31, 2022. Cash provided in 2023 was from November 2022 financing on Nasdaq and April 2023 Public Offering.

 

The Company anticipates that its cash and cash equivalents will provide sufficient liquidity for at least twelve months, however, the Company may have capital requirements in excess of its currently available resources in order to advance all it its programs. The actual amount of cash that the Company will need to operate is subject to many factors, including, but not limited to, the timing, design and conduct of clinical trials. The Company is dependent upon significant future financing to provide the cash necessary to execute its current operations, including the commercialization of any of its drug candidates. 

 

In the event the Company’s plans change, its assumptions change or prove inaccurate, or its capital resources in addition to projected cash flow, if any, prove to be insufficient to fund operations, the Company may be required to seek additional financing. There can be no assurance that the Company will have sufficient financing to meet its future capital requirements or that additional financing will be available on terms acceptable to the Company in the future.

 

Capital Management

 

The Company manages its capital to maintain its ability to continue as a going concern and to provide returns to shareholders and benefits to other stakeholders. The capital structure of the Company consists of cash and equity comprised of issued capital, shares issuable, warrants reserve and share-based payment reserve.

 

The Company manages its capital structure and makes adjustments to it in light of economic conditions. The Company, upon approval from its Board of Directors, will balance its overall capital structure through new share issuances or by undertaking other activities as deemed appropriate under the specific circumstances.

 

The Company is not subject to externally imposed capital requirements and the Company’s overall strategy with respect to capital risk management remains unchanged from the year ended October 31, 2022.

 

Off Balance Sheet Arrangements

 

There are no off-balance sheet arrangements to which the Company is committed.

 

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CLEARMIND MEDICINE INC.

Management’s Discussion and Analysis

For the Three and Nine Months Ended July 31, 2023

 

Transactions With Related Parties

 

a.Compensation to key management personnel

 

(i)The compensation to key management personnel for employment services they provide to the Company is as follows:

 

   Three months ended   Three months ended   Nine months ended   Nine months ended 
   July 31,   July 31,   July 31,   July 31, 
   2023   2022   2023   2022 
                 
Officers:                
Consulting fees  $79,950   $82,934   $282,668   $278,438 
Share based compensation   28,368    437,715    107,089    667,916 
   $108,318   $520,648   $389,757   $946,354 
Directors:                    
Directors’ fees  $41,021   $84,548   $121,998   $119,909 
Share based compensation   28,558    6,236    106,682    24,978 
   $69,579   $90,785   $228,680   $144,887 

 

(ii)Balances with related parties

 

   July 31,   October 31, 
   2023   2022 
Amounts owed to officers  $27,834   $136,149 
Amounts owed to directors   13,757    70,345 
   $41,591   $206,494 

 

b.On March 7, 2022, the Company signed an agreement with SciSparc Ltd (“SciSparc”), pursuant to which the Company and SciSparc agreed to cooperate in conducting a feasibility study using certain molecules developed by each party (the “Cooperation Agreement”). Certain of the Company’s officers and directors currently operate, manage or are engaged as officers and/or directors of SciSparc, which may have similar or different objectives than the Company’s. Such activities could detract from the time these people have to allocate to the Company’s affairs. To date, no determination has been made to pursue the joint venture and the development of the research activities with SciSparc remains in a very early stage. For the nine months ended July 31, 2023, the Company received $0 as a reimbursement for research and development expenses conducted within the framework of the Cooperation Agreement. As of July 31, 2023, $126,661 is owed to the Company by SciSparc.

 

c.On July 1, 2021, the Company entered into a lease agreement (“2021 Lease”) with SciSparc, a related party,and a third party for a total area of approximately 240m2 , of which the Company occupies approximately 120m2 for the Company’s offices, in Tel Aviv, Israel. The lease expired on June 30, 2023. The Company, SciSparc and the third party have an option to extend the 2021 Lease for an additional three-year period. The Company’s base rent was ILS11,000 per month ($3,080) during the term of the 2021 Lease. The lease liability was discounted using the Company’s estimated incremental borrowing rate of 20%. On December 31, 2021, the third party elected to leave the office space, and a new lease agreement was signed with the Company and the related party. As a result, the Company’s base rent was increased to ILS 18,200 per month ($5,094).
   
  As of July 31, 2023 the Company and SciSparc are in the process of negotiating the terms of a new lease contract but that as of the balance sheet date no definitive agreement has been entered into.

 

9

 

 

CLEARMIND MEDICINE INC.

Management’s Discussion and Analysis

For the Three and Nine Months Ended July 31, 2023

 

Financial Instruments and Risk Management

 

(a)Fair Values

 

Assets and liabilities measured at fair value on a recurring basis were presented on the Company’s statement of financial position as of July 31, 2023, as follows:

 

   Fair Value Measurements Using     
   Quoted prices
in active markets
for identical
instruments
(Level 1)
   Significant
other
observable
inputs
(Level 2)
   Significant
unobservable
inputs
(Level 3)
   Balance
July 31,
2023
 
Short-term investment  $122,779   $   $              –   $122,779 
Derivative warrants liability       1,313,168        1,313,168 

 

Assets and liabilities measured at fair value on a recurring basis were presented on the Company’s statement of financial position as of October 31, 2022, as follows: 

 

   Fair Value Measurements Using     
   Quoted prices
in active markets
for identical
instruments
(Level 1)
   Significant
other
observable
inputs
(Level 2)
   Significant
unobservable
inputs
(Level 3)
   Balance
October 31,
2022
 
Short-term investment  $193,750   $          –   $             –   $193,750 
Derivative liability       290,569        290,569 

 

The fair values financial instruments, which include cash, amounts receivable, accounts payable and accrued liabilities, and amounts due to related parties, approximate their carrying values due to the relatively short-term maturity of these instruments.

 

(b)Credit Risk

 

Financial instruments that potentially subject the Company to a concentration of credit risk consist primarily of cash. The Company limits its exposure to credit loss by placing its cash with high credit quality financial institutions. The carrying amount of financial assets represents the maximum credit exposure.

 

(c)Foreign Exchange Rate Risk

 

Foreign currency risk is the risk that the fair value of future cash flows of a financial instrument will fluctuate due to changes in foreign exchange rates. The Company is exposed to foreign currency risk to the extent that monetary assets and liabilities are denominated in a foreign currency. The Company’s subsidiary operates in Israel and has certain monetary financial instruments denominated in New Israeli Shekel and CAD. The Company has not entered into foreign exchange rate contracts to mitigate this risk.

 

The following table indicates the impact of foreign currency exchange risk on net working capital as at July 31, 2023. The table below also provides a sensitivity analysis of a 10% strengthening of the foreign currency against functional currencies identified which would have increased (decreased) the Company’s net loss by the amounts shown in the table below. A 10% weakening of the foreign currency against the functional currencies would have had the equal but opposite effect as of July 31, 2023.

 

Cash  $253,952 
Amounts receivable   108,255 
Accounts payable and accrued liabilities   (218,499)
Due to related parties   (41,591)
Total foreign currency financial assets and liabilities  $(102,117)
      
Impact of a 10% strengthening or weakening of foreign exchange rate  $10,212 

 

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CLEARMIND MEDICINE INC.

Management’s Discussion and Analysis

For the Three and Nine Months Ended July 31, 2023

 

(d)Interest Rate Risk

 

Interest rate risk is the risk that the fair value of future cash flows of a financial instrument will fluctuate because of changes in market interest rates. The Company is not exposed to significant interest rate risk as it does not have any liabilities with variable rates.

 

(e)Liquidity Risk

 

Liquidity risk is the risk that the Company will not be able to meet its financial obligations as they fall due. The Company’s objective to managing liquidity risk is to ensure that it has sufficient liquidity available to meet its liabilities when due. The Company relies on raising debt or equity financing in a timely manner.

 

The following amounts are the contractual maturities of financial liabilities as of July 31, 2023, and October 31, 2022:

 

July 31, 2023  Total   Within
1 year
   Within
2-5 years
 
             
Accounts payable and accrued liabilities  $306,011   $306,011   $             – 
Due to related parties   41,591    41,591     
Derivative warrants liability   1,313,168    1,313,168     
   $1,660,770   $1,660,770   $ 

 

October 31, 2022  Total   Within
1 year
   Within
2-5 years
 
             
Accounts payable and accrued liabilities  $1,396,960   $1,396,960   $               – 
Due to related parties   206,494    206,494     
Derivative liability   290,569    290,569      
Lease liability   38,390    38,390      
   $1,932,413   $1,932,413   $ 

 

Accounting Standards Issued But Not Yet Effective

 

A number of new standards, and amendments to standards and interpretations, are not yet effective for the nine months ended July 31, 2023, and have not been early adopted in preparing these condensed interim consolidated financial statements. These new standards, and amendments to standards and interpretations are either not applicable or are not expected to have a significant impact on the Company’s condensed interim consolidated financial statements.

 

Significant Accounting Estimates and Judgments

 

The preparation of condensed interim consolidated financial statements in accordance with IFRS requires management to make judgments, estimates, and assumptions that affect the application of policies and reported amounts of assets, liabilities, income, and expenses. The estimates and associated assumptions are based on historical experience and various other factors that are believed to be reasonable under the circumstances, the results of which form the basis of making the judgments about carrying values of assets and liabilities that are not readily apparent from other sources. Actual results may differ from these estimates.

 

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CLEARMIND MEDICINE INC.

Management’s Discussion and Analysis

For the Three and Nine Months Ended July 31, 2023

 

Significant Estimates

 

Share-based Compensation

 

Fair values are determined using the Black-Scholes option pricing model. Estimating fair value requires determining the most appropriate valuation model for a grant of equity instruments, which is dependent on the terms and conditions of the grant. Option-pricing models require the use of highly subjective estimates and assumptions including the expected stock price volatility. Changes in the underlying assumptions can materially affect the fair value estimates and, therefore, existing models do not necessarily provide reliable measurement of the fair value of the Company’s stock options.

 

Warrant Liability

 

The Company uses the Black-Scholes option-pricing model to estimate fair value of options and the warrant liability at each reporting date. The key assumptions used in the model are the expected future volatility in the price of the Company’s shares and the expected life of the options and warrants.

 

Significant Judgments

 

The critical judgments that the Company’s management has made in the process of applying the Company’s accounting policies that have the most significant effect on the amounts recognized in the Company’s consolidated financial statements are as follows:

 

Going Concern

 

The application of the going concern assumption which requires management to take into account all available information about the future, which is at least but not limited to, 12 months from the year end of the reporting period. The Company is aware that material uncertainties related to events or conditions may cast significant doubt upon the Company’s ability to continue as a going concern.

 

Additional Disclosure for Companies Without Significant Revenue

 

An analysis of material components of the Company’s general and administrative expenses is disclosed in the condensed interim consolidated financial statements for the nine and three-months ended July 31, 2023, to which this MD&A relates.

 

Disclosure of Outstanding Share Data

 

Authorized share capital consists of unlimited number of common shares without par value.

 

As of July 31, 2023, and September 13, 2023, the Company had 7,118,213 and 7,137,096 common shares issued and outstanding, respectively.

 

As of July 31, 2023, and September 13, 2023, the Company had 144,333 stock options outstanding.

 

As of July 31, 2023, and September 13, 2023, the Company had 4,881,895 and 4,815,650 share purchase warrants outstanding, respectively.

 

As of July 31, 2023, and September 13, 2023, the Company had 78,088 and 62,539 RSU’s outstanding.

 

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CLEARMIND MEDICINE INC.

Management’s Discussion and Analysis

For the Three and Nine Months Ended July 31, 2023

 

Risks and Uncertainties

 

The Company business, and investing in the Company’s securities, are subject to numerous risks, as more fully described in the section entitled “Risk Factors” beginning on page 9 and other risk factors contained in the Company’s Annual Information Form filed in SEDAR on December 1, 2022. If any of these risks actually occur, the Company’s business, financial condition or results of operations would likely be materially adversely affected. In each case, the trading price of the Company’s securities would likely decline, and investors may lose all or part of their investment. The following is a summary of some of the principal risks the Company faces:

 

The Company has incurred losses since its inception. The Company anticipated that it will incur significant losses for the foreseeable future, and the Company may never achieve or maintain profitability.

 

  The Company’s financial statements contain an explanatory paragraph regarding substantial doubt about the Company’s ability to continue as a going concern.
     
  If the Company is unable to establish sales and marketing capabilities or enter into agreements to sell and market any product candidates, the Company may not be successful in commercializing those product candidates.
     
  If the Company is unable to maintain effective proprietary rights for the Company’s product candidates or any future product candidates, the Company may not be able to compete effectively in its markets.

 

 

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