0001892134-24-000002.txt : 20240214 0001892134-24-000002.hdr.sgml : 20240214 20240214135547 ACCESSION NUMBER: 0001892134-24-000002 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20231231 FILED AS OF DATE: 20240214 DATE AS OF CHANGE: 20240214 EFFECTIVENESS DATE: 20240214 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Frazier Life Sciences Management, L.P. CENTRAL INDEX KEY: 0001892134 ORGANIZATION NAME: IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-22504 FILM NUMBER: 24635760 BUSINESS ADDRESS: STREET 1: 1001 PAGE MILL ROAD STREET 2: BUILDING 4, SUITE B CITY: PALO ALTO STATE: CA ZIP: 94304 BUSINESS PHONE: (650) 325-5156 MAIL ADDRESS: STREET 1: 1001 PAGE MILL ROAD STREET 2: BUILDING 4, SUITE B CITY: PALO ALTO STATE: CA ZIP: 94304 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false false false 0001892134 XXXXXXXX 12-31-2023 12-31-2023 Frazier Life Sciences Management, L.P.

1001 PAGE MILL ROAD BUILDING 4, SUITE B PALO ALTO CA 94304

13F HOLDINGS REPORT 028-22504 000317522 801-122904 N Steve R. Bailey (206) 621-7200 Steve R. Bailey Seattle WA 02-12-2024 0 49 1870349025 false INFORMATION TABLE 2 flsmq42023form13f4.xml 89BIO INC COM 282559103 22340000 2000000 SH SOLE 2000000 0 0 ACADIA PHARMACEUTICALS INC COM 004225108 22885011 730917 SH SOLE 730917 0 0 ACLARIS THERAPEUTICS INC COM 00461U105 277596 264377 SH SOLE 264377 0 0 AEROVATE THERAPEUTICS INC COM 008064107 27266140 1204867 SH SOLE 1204867 0 0 AGIOS PHARMACEUTICALS INC COM 00847X104 11650907 523166 SH SOLE 523166 0 0 ALPINE IMMUNE SCIENCES INC COM 02083G100 59677012 3131008 SH SOLE 3131008 0 0 AN2 THERAPEUTICS INC COM 037326105 28458336 1388889 SH SOLE 1388889 0 0 ANAPTYSBIO INC COM 032724106 19271574 899700 SH SOLE 899700 0 0 APELLIS PHARMACEUTICALS INC COM 03753U106 52985977 885165 SH SOLE 885165 0 0 APOGEE THERAPEUTICS INC COM 03770N101 11176000 400000 SH SOLE 400000 0 0 ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 28308469 8764232 SH SOLE 8764232 0 0 ARVINAS INC COM 04335A105 11744224 285331 SH SOLE 285331 0 0 AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 24129759 3746857 SH SOLE 3746857 0 0 BLUEBIRD BIO INC COM 09609G100 2359672 1709907 SH SOLE 1709907 0 0 BRIDGEBIO PHARMA INC COM 10806X102 110046561 2725949 SH SOLE 2725949 0 0 CEREVEL THERAPEUTICS HLDNG I COM 15678U128 16663200 393000 SH SOLE 393000 0 0 COGENT BIOSCIENCES INC COM 19240Q201 11732170 1995267 SH SOLE 1995267 0 0 CRINETICS PHARMACEUTICALS IN COM 22663K107 14142445 397483 SH SOLE 397483 0 0 DECIPHERA PHARMACEUTICALS IN COM 24344T101 16481634 1021800 SH SOLE 1021800 0 0 DISC MEDICINE INC COM 254604101 45341600 785000 SH SOLE 785000 0 0 DYNE THERAPEUTICS INC COM 26818M108 15758372 1184840 SH SOLE 1184840 0 0 EDGEWISE THERAPEUTICS INC COM 28036F105 29179201 2667203 SH SOLE 2667203 0 0 GRITSTONE BIO INC COM 39868T105 2102991 1030878 SH SOLE 1030878 0 0 HILLEVAX INC COM 43157M102 156992626 9781472 SH SOLE 9781472 0 0 INTELLIA THERAPEUTICS INC COM 45826J105 6210325 203684 SH SOLE 203684 0 0 KALVISTA PHARMACEUTICALS INC COM 483497103 44373102 3622294 SH SOLE 3622294 0 0 KRYSTAL BIOTECH INC COM 501147102 122628348 988460 SH SOLE 988460 0 0 MACROGENICS INC COM 556099109 23104392 2401704 SH SOLE 2401704 0 0 MADRIGAL PHARMACEUTICALS INC COM 558868105 16059160 69406 SH SOLE 69406 0 0 MERUS N V COM N5749R100 20528173 746479 SH SOLE 746479 0 0 MIRATI THERAPEUTICS INC COM 60468T105 4700000 80000 SH SOLE 80000 0 0 MIRUM PHARMACEUTICALS INC COM 604749101 191743972 6495392 SH SOLE 6495392 0 0 NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES N62509109 135511145 12131705 SH SOLE 12131705 0 0 NEWAMSTERDAM PHARMA COMPANY *W EXP 11/22/202 N62509117 1566042 500333 SH SOLE 500333 0 0 ORIC PHARMACEUTICALS INC COM 68622P109 19714266 2142855 SH SOLE 2142855 0 0 PHATHOM PHARMACEUTICALS INC COM 71722W107 92297717 10109279 SH SOLE 10109279 0 0 REVOLUTION MEDICINES INC COM 76155X100 28607009 997455 SH SOLE 997455 0 0 RHYTHM PHARMACEUTICALS INC COM 76243J105 109008845 2371304 SH SOLE 2371304 0 0 ROCKET PHARMACEUTICALS INC COM 77313F106 45644700 1523013 SH SOLE 1523013 0 0 SAVARA INC COM 805111101 18800000 4000000 SH SOLE 4000000 0 0 SILENCE THERAPEUTICS PLC ADS 82686Q101 15305975 881173 SH SOLE 881173 0 0 SOLENO THERAPEUTICS INC COM 834203309 18713714 464937 SH SOLE 464937 0 0 STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106 12928664 317190 SH SOLE 317190 0 0 TARSUS PHARMACEUTICALS INC COM 87650L103 36197422 1787527 SH SOLE 1787527 0 0 THESEUS PHARMACEUTICALS INC COM 88369M101 8578107 2118051 SH SOLE 2118051 0 0 TREVI THERAPEUTICS INC COM 89532M101 9890661 7381090 SH SOLE 7381090 0 0 TYRA BIOSCIENCES INC COM 90240B106 14215917 1026420 SH SOLE 1026420 0 0 VAXCYTE INC COM 92243G108 73124634 1164405 SH SOLE 1164405 0 0 VERONA PHARMA PLC SPONSORED ADS 925050106 59925258 3014349 SH SOLE 3014349 0 0