The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACLARIS THERAPEUTICS INC COM 00461U105 7,040 408,329 SH   SOLE   408,329 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 37,546 4,185,757 SH   SOLE   4,185,757 0 0
ANAPTYSBIO INC COM 032724106 22,259 899,700 SH   SOLE   899,700 0 0
APTINYX INC COM 03836N103 4,275 1,883,244 SH   SOLE   1,883,244 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 162,443 8,434,232 SH   SOLE   8,434,232 0 0
ARVINAS INC COM 04335A105 18,193 270,331 SH   SOLE   270,331 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 15,624 3,746,857 SH   SOLE   3,746,857 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 6,501 951,814 SH   SOLE   951,814 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 26,483 603,521 SH   SOLE   603,521 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 1,955 55,835 SH   SOLE   55,835 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 44,369 2,712,041 SH   SOLE   2,712,041 0 0
COGENT BIOSCIENCES INC COM 19240Q201 19,862 2,651,754 SH   SOLE   2,651,754 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 31,055 1,414,823 SH   SOLE   1,414,823 0 0
EPIZYME INC COM 29428V104 850 739,369 SH   SOLE   739,369 0 0
ESSA PHARMA INC COM NEW 29668H708 4,282 692,910 SH   SOLE   692,910 0 0
FRAZIER LIFESCIENCES ACQU CO UNIT 12/09/2025 G3710A121 14,995 1,501,000 SH   SOLE   1,501,000 0 0
GRACELL BIOTECHNOLOGIES INC SPONSORED ADS 38406L103 8,029 3,445,973 SH   SOLE   3,445,973 0 0
GRITSTONE BIO INC COM 39868T105 21,578 5,237,348 SH   SOLE   5,237,348 0 0
IMAGO BIOSCIENCES INC COM 45250K107 57,256 2,971,274 SH   SOLE   2,971,274 0 0
IMMUNOVANT INC COM 45258J102 3,228 585,759 SH   SOLE   585,759 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 14,802 203,684 SH   SOLE   203,684 0 0
IVERIC BIO INC COM 46583P102 40,755 2,421,563 SH   SOLE   2,421,563 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 23,174 1,572,192 SH   SOLE   1,572,192 0 0
KRYSTAL BIOTECH INC COM 501147102 57,640 866,250 SH   SOLE   866,250 0 0
MERUS N V COM N5749R100 16,630 628,979 SH   SOLE   628,979 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 78,543 3,566,912 SH   SOLE   3,566,912 0 0
MOLECULAR TEMPLATES INC COM 608550109 4,740 1,374,047 SH   SOLE   1,374,047 0 0
NABRIVA THERAPEUTICS PLC SHS G63637113 179 425,650 SH   SOLE   425,650 0 0
PARDES BIOSCIENCES INC COM 69945Q105 15,025 2,081,007 SH   SOLE   2,081,007 0 0
PASSAGE BIO INC COM 702712100 15,529 5,009,219 SH   SOLE   5,009,219 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107 79,311 5,827,415 SH   SOLE   5,827,415 0 0
REPLIMUNE GROUP INC COM 76029N106 12,171 716,762 SH   SOLE   716,762 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 2,011 156,000 SH   SOLE   156,000 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 75,067 2,342,198 SH   SOLE   2,342,198 0 0
SILENCE THERAPEUTICS PLC ADS 82686Q101 16,742 881,173 SH   SOLE   881,173 0 0
SUTRO BIOPHARMA INC COM 869367102 14,603 1,776,479 SH   SOLE   1,776,479 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 55,536 3,195,403 SH   SOLE   3,195,403 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103 23,837 1,417,157 SH   SOLE   1,417,157 0 0
TRICIDA INC COM 89610F101 17,115 2,082,093 SH   SOLE   2,082,093 0 0
TYRA BIOSCIENCES INC COM 90240B106 14,206 1,327,665 SH   SOLE   1,327,665 0 0
VAXCYTE INC COM 92243G108 55,776 2,309,554 SH   SOLE   2,309,554 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 32,164 1,739,530 SH   SOLE   1,739,530 0 0