Composition of Certain Consolidated Financial Statement Line Items - Accrued expenses and other current liabilities (Details) - USD ($) $ in Thousands	Mar. 31, 2026	Dec. 31, 2025
Composition of Certain Consolidated Financial Statement Line Items
Accrued compensation	$ 6,368	$ 12,434
Accrued research and development expenses	8,349	12,404
Accrued clinical expenses	23,067	15,791
Accrued professional services	7,192	4,470
Accrued other liabilities	1,577	1,444
Total accrued expenses and other current liabilities	$ 46,553	$ 46,543

Carrying amount as of the balance sheet date of current portion of accrued clinical expenses.

No definition available.

Name:	gpcr_AccruedClinicalExpensesCurrent
Namespace Prefix:	gpcr_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

The amount of current portion of accrued expenses and other liabilities as at the end of the reporting period.

+ References

No definition available.

+ Details

Name:	gpcr_AccruedExpensesAndOtherLiabilitiesCurrent
Namespace Prefix:	gpcr_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Carrying amount as of the balance sheet date of current portion of accrued research and development expenses.

+ References

No definition available.

+ Details

Name:	gpcr_AccruedResearchAndDevelopmentExpensesCurrent
Namespace Prefix:	gpcr_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- References

No definition available.

+ Details

Name:	srt_ItemsIncludedInConsolidatedStatementOfFinancialConditionAbstract
Namespace Prefix:	srt_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

- Definition

Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 210
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(20))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1

+ Details

Name:	us-gaap_AccruedProfessionalFeesCurrent
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Total of the carrying values as of the balance sheet date of obligations incurred through that date and payable for obligations related to services received from employees, such as accrued salaries and bonuses, payroll taxes and fringe benefits. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

+ References

+ Details

Name:	us-gaap_EmployeeRelatedLiabilitiesCurrent
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Amount of expenses incurred but not yet paid classified as other, due within one year or the normal operating cycle, if longer.

+ References

+ Details

Name:	us-gaap_OtherAccruedLiabilitiesCurrent
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant