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Related Party Transactions - Additional Information (Details) - USD ($)	1 Months Ended	3 Months Ended		6 Months Ended
	Mar. 31, 2022	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Related Party Transaction [Line Items]
Contingent payment recorded as in-process research and development				$ 2,500,000
Accounts payable		$ 6,033,000		6,033,000		$ 1,024,000
Accrued expenses		6,419,000		6,419,000		9,164,000
Frazier
Related Party Transaction [Line Items]
Due to related parties		8,000		8,000		22,000
Shared operating expenses		8,000	$ 200,000	34,000	$ 400,000
Mountain Field
Related Party Transaction [Line Items]
Shared operating expenses		0	$ 0	0	$ 5,000
Takeda
Related Party Transaction [Line Items]
Contingent payment recorded as in-process research and development	$ 2,500,000
Takeda \| TSA
Related Party Transaction [Line Items]
Research and development expenses		200,000		1,600,000
Accounts payable		1,600,000		1,600,000
Accrued expenses		$ 800,000		$ 800,000		$ 4,900,000