Organization, Basis of Presentation and Summary of Significant Accounting Policies - Summary of Significant Unobservable Inputs Used in Fair Value Measurements (Details)	12 Months Ended
	Dec. 31, 2021 $ / shares	Jun. 30, 2022 $ / shares
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Transaction prices per share		$ 0.0000595
Takeda Warrants | Discount Rate
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Warrants measurement input	20
Takeda Warrants | Minimum
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Transaction prices per share	$ 11.83
Estimated time to liquidity	2 months 12 days
Takeda Warrants | Maximum
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Transaction prices per share	$ 12.54
Estimated time to liquidity	1 year 9 months
August 2021 Notes | Minimum
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Estimated time to liquidity	2 months 12 days
August 2021 Notes | Minimum | Discount Rate
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Notes measurement input	19
August 2021 Notes | Minimum | Volatility
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Notes measurement input	80
August 2021 Notes | Minimum | Risk-Free Interest Rate
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Notes measurement input	0.1
August 2021 Notes | Maximum
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Estimated time to liquidity	1 year 9 months
August 2021 Notes | Maximum | Discount Rate
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Notes measurement input	20
August 2021 Notes | Maximum | Volatility
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Notes measurement input	100
August 2021 Notes | Maximum | Risk-Free Interest Rate
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Notes measurement input	0.7