X0407 4 2023-03-17 0001830214 Ginkgo Bioworks Holdings, Inc. DNA 0001883686 Fallon Marie E. C/O GINKGO BIOWORKS HOLDINGS, INC. 27 DRYDOCK AVENUE BOSTON MA 02210 1 See remarks 0 Restricted Stock Units 2023-03-17 4 A 0 180000 A Class A Common Stock 180000 180000 D Restricted Stock Units Class A Common Stock 385012 385012 D Each restricted stock unit (the "RSU") represents a contingent right to receive one share of the Issuer's Class A Common Stock. The RSUs vest in 48 equal monthly installments beginning on April 1, 2023. Represents RSUs granted prior to the business combination of Soaring Eagle Acquisition Corp. and Ginkgo Bioworks, Inc. in September 2021 (the "Merger"), which became contingent rights to acquire equity securities of the Issuer upon consummation of the Merger. At the time of grant, the RSUs were subject to both a service-based vesting condition and a performance-based vesting condition. On November 17, 2021, the board of directors of the Issuer modified the vesting terms of RSUs, such that the Merger was deemed to have satisfied the performance condition for vesting effective as of March 15, 2022. Chief Accounting Officer /s/ Karen Tepichin, Attorney-in-Fact 2023-03-24