X0306 4 2021-09-14 0 0001645569 DICE Therapeutics, Inc. DICE 0001882035 Robertson Scott M. C/O DICE THERAPEUTICS, INC. 279 E. GRAND AVENUE, SUITE 300, LOBBY B SOUTH SAN FRANCISCO CA 94080 0 1 0 0 CFO & CBO Common Stock 216750 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 7191 0.00 A 2031-09-14 Common Stock 7191 7191 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 771 0.00 A 2031-09-14 Common Stock 771 771 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 20751 0.00 A 2031-09-14 Common Stock 20751 20751 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 2688 0.00 A 2031-09-14 Common Stock 2688 2688 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 9095 0.00 A 2031-09-14 Common Stock 9095 9095 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 16595 0.00 A 2031-09-14 Common Stock 16595 16595 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 15000 0.00 A 2031-09-14 Common Stock 15000 15000 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 9750 0.00 A 2031-09-14 Common Stock 9750 9750 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 920 0.00 A 2031-09-14 Common Stock 920 920 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 20000 0.00 A 2031-09-14 Common Stock 20000 20000 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 2500 0.00 A 2031-09-14 Common Stock 2500 2500 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 7500 0.00 A 2031-09-14 Common Stock 7500 7500 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 11250 0.00 A 2031-09-14 Common Stock 11250 11250 D Stock Option (right to buy) 17.00 2021-09-14 4 A 0 5000 0.00 A 2031-09-14 Common Stock 5000 5000 D The number of shares of Common Stock reported in the Reporting Holder's Form 3 reflected the conversion of derivative securities based on the midpoint of the Issuer's initial public offering range of $16.00 per share. The number of shares of Common Stock reflected in this Form 4 reflects the adjusted number of shares issued based on the higher initial public offering price of $17.00 per share, and does not reflect a disposition of shares. Certain of the shares are subject to the Issuer's right of repurchase if underlying vesting conditions are not met. The option is fully vested and exercisable. The option vests as to 1/48th of the total shares monthly, beginning December 1, 2017, subject to the Reporting Holder's continuing employment with the Registrant. The option vests as to 1/48th of the total shares monthly, beginning February 28, 2019, subject to the Reporting Holder's continuing employment with the Registrant. The option vests as to 1/48th of the total shares monthly, beginning August 27, 2020, subject to the Reporting Holder's continuing employment with the Registrant. The option vests as to 1/48th of the total shares monthly, beginning January 1, 2021, subject to the Reporting Holder's continuing employment with the Registrant. The option vests as to 1/48th of the total shares monthly, beginning August 2, 2021, subject to the Reporting Holder's continuing employment with the Registrant. The option vests as to 1/48th of the total shares monthly, beginning August 20, 2021, subject to the Reporting Holder's continuing employment with the Registrant. /s/ J. Kevin Judice as attorney-in-fact for Scott M. Robertson 2021-09-16