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Basis of Presentation and Summary of Significant Accounting Policies - Additional Information (Details)
1 Months Ended 3 Months Ended 6 Months Ended
Jun. 30, 2025
USD ($)
$ / shares
shares
Apr. 30, 2025
USD ($)
Sep. 30, 2024
USD ($)
Jul. 31, 2024
USD ($)
May 31, 2024
USD ($)
Sep. 30, 2023
USD ($)
Jul. 31, 2023
USD ($)
Sep. 30, 2022
USD ($)
Jun. 30, 2025
USD ($)
$ / shares
Mar. 31, 2025
USD ($)
Jun. 30, 2024
USD ($)
Mar. 31, 2024
USD ($)
Jun. 30, 2025
USD ($)
Segment
$ / shares
Jun. 30, 2024
USD ($)
Dec. 31, 2024
USD ($)
Accounting Policies [Line Items]                              
Net loss                 $ 6,462,000 $ 10,649,000 $ 14,435,000 $ 16,617,000 $ 17,100,000 $ 31,100,000  
Cash flows used in operating activities                         18,223,000 31,977,000  
Accumulated deficit $ 222,887,000               222,887,000       222,887,000   $ 205,776,000
Cash, cash equivalents and investments 71,200,000               71,200,000       $ 71,200,000    
Number of operating segments | Segment                         1    
Number of reportable Segments | Segment                         1    
Assumed dividend yield                         $ 0    
Cash and cash equivalents 18,220,000               18,220,000       18,220,000   21,351,000
Investments 53,000,000               $ 53,000,000       53,000,000   $ 67,300,000
Maximum amount eligible to receive under cost-reimbursement contract award 18,300,000             $ 17,800,000              
Award reduction amount 9,000,000                            
Maximum amount eligible to receive under cost-reimbursement cumulative contract award after reduction $ 9,300,000                            
Net unrealized gain (loss) on available-for-sale investments                         $ (300,000) $ (300,000)  
Exchange of common stock for pre-funded warrants, shares | shares 2,952,000                            
Nominal exercise price | $ / shares $ 0.00001               $ 0.00001       $ 0.00001    
NIAID Contract                              
Accounting Policies [Line Items]                              
Maximum amount eligible to receive under cost-reimbursement contract award $ 18,300,000             17,800,000              
Government contract fund increased amount   $ 500,000     $ 3,800,000   $ 700,000                
UGARF                              
Accounting Policies [Line Items]                              
Grant award amount       $ 200,000       $ 1,400,000              
BMGF                              
Accounting Policies [Line Items]                              
Grant award amount     $ 2,000,000     $ 1,800,000