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Income Taxes - Provision for Income Taxes Differs from Tax Expense (Details) - USD ($)
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Income Tax Disclosure [Abstract]    
Federal tax benefit at statutory rate $ (10,777,000) $ (13,593,000)
State tax benefit at statutory rate, net of federal tax benefit (3,892,000) (4,917,000)
Change in valuation allowance 16,289,000 20,047,000
Research and development tax credits (1,980,000) (2,030,000)
Other 360,000 493,000
Provision for income taxes $ 0 $ 0