SCHEDULE 13G 0001968053 XXXXXXXX LIVE Ordinary Shares, no par value 12/31/2022 0001871321 Alpha Tau Medical Ltd. M0740A108 Kiryat HaMada St. 5 Jerusalem L3 9777605 Rule 13d-1(d) Uzi Sofer L3 13702361.00 0.00 13702361.00 0.00 13702361.00 N 15.8 IN Alpha Tau Medical Ltd. Kiryat HaMada St. 5, Jerusalem, Israel 9777605 Uzi Sofer (the "Reporting Person") The principal business address of the Reporting Person is c/o Alpha Tau Medical Ltd., Kiryat HaMada St. 5, Jerusalem 9777605, Israel. The Reporting Person is a citizen of the State of Israel. Y The Reporting Person is the beneficial owner of 13,702,361 Ordinary Shares, which includes 2,187,047 Ordinary Shares underlying restricted stock units vested and stock options exercisable within 60 days of the date hereof. The ownership information presented herein represents beneficial ownership of Ordinary Shares of the Issuer as of the date hereof, based upon 84,819,996 Ordinary Shares outstanding as of June 20, 2025, as disclosed in the Issuer's Registration Statement on Form F-3 filed with the Securities and Exchange Commission on June 23, 2025. 15.8% 13,702,361 0 13,702,361 0 Y Y Y Y Y Y Uzi Sofer /s/ Uzi Sofer 07/24/2025